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心血管疾病与新冠病毒病:一项系统综述。

Cardiovascular disease and covid-19: A systematic review.

作者信息

Krishna B A, Metaxaki M, Sithole N, Landín P, Martín P, Salinas-Botrán A

机构信息

Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

Department of Infectious Diseases, Cambridge University, Cambridge, United Kingdom.

出版信息

Int J Cardiol Heart Vasc. 2024 Aug 2;54:101482. doi: 10.1016/j.ijcha.2024.101482. eCollection 2024 Oct.

Abstract

BACKGROUND

Cardiovascular complications of COVID-19 are numerous and aspects of this phenomenon are not well known. The main objective of this manuscript is a systematic review of the acute and chronic cardiovascular complications secondary to COVID-19.

METHODS

A systematic review of the literature through Medline via PubMed was conducted (2020-2024).

RESULTS

There is a plethora of effects of COVID-19 on the heart in the acute setting. Here we discuss pathophysiology, myocardial infarctions, heart failure, Takotsubo Cardiomyopathy, myocardial injury, myocarditis and arrhythmias that are caused by COVID-19. Additionally, these cardiovascular injuries can linger and may be an underlying cause of some Long COVID symptoms.

CONCLUSIONS

Cardiovascular complications of COVID-19 are numerous and life-threatening. Long COVID can affect cardiovascular health. Microclotting induced by SARS-CoV-2 infection could be a therapeutic target for some aspects of Long Covid.

摘要

背景

新型冠状病毒肺炎(COVID-19)的心血管并发症众多,且这一现象的诸多方面尚不为人所知。本手稿的主要目的是对COVID-19继发的急性和慢性心血管并发症进行系统综述。

方法

通过PubMed对Medline进行文献系统综述(2020 - 2024年)。

结果

在急性期,COVID-19对心脏有诸多影响。在此,我们讨论由COVID-19引起的病理生理学、心肌梗死、心力衰竭、应激性心肌病、心肌损伤、心肌炎和心律失常。此外,这些心血管损伤可能会持续存在,并且可能是一些新冠后症状的潜在原因。

结论

COVID-19的心血管并发症众多且危及生命。新冠后症状可能影响心血管健康。由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染引起的微凝血可能是新冠后症状某些方面的治疗靶点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25f7/11345335/6280a10f2102/gr1.jpg

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