Khatri Surya, Albright J Alex, Byrne Rory A, Quinn Matthew, Zhu Angela S, Arcand Paul-Hugo, Daniels Alan H, Owens Brett D
Warren Alpert Medical School, Brown University, Providence, Rhode Island.
Department of Orthopaedic Surgery, Warren Alpert Medical School, Brown University, Providence, Rhode Island.
Sports Health. 2024 Aug 27:19417381241273453. doi: 10.1177/19417381241273453.
This study explores the association between vitamin D deficiency and distal biceps tendon injuries, illustrating that, although vitamin D deficiency is associated with prolonged hospital stays and various musculoskeletal problems, its connection to distal biceps tendon injuries is unknown.
Vitamin D deficiency is associated with an elevated risk of distal biceps injury but not with increased rates of subsequent surgery or revision surgery.
Case-control study.
Level 3.
A 1:1 matched retrospective comparative study of 336,320 vitamin-D-deficient patients was performed using PearlDiver data (between January 1, 2011 and October 31, 2018). Cohorts, with a mean age of 55.7 ± 13.2 years, underwent multivariate logistic regression to calculate distal biceps tendon injury and surgical repair incidence according to age and sex, while controlling for demographics and comorbidities.
The 1-year incidence of distal biceps tendinopathy in vitamin-D-deficient patients was 118 per 100,000 person-years (95% CI) compared with 44.3 per 100,000 person-years in matched controls. Male patients with vitamin D deficiency were at a greater risk for distal biceps tendinopathy after 1 and 2 years (adjusted odds ratio [aOR] = 2.81, 2.08-3.83; aOR = 2.80, 2.21-3.56). Female patients were also at a greater risk after both years (aOR = 1.69, 1.27-2.27; aOR = 1.57, 1.26-1.96). Vitamin D deficiency was not associated with an elevated risk of surgical repair or revision surgery.
In a nationwide cohort, a diagnosis of vitamin D deficiency elevated the risk of distal biceps tendinopathy but did not raise the rate of surgical repair or revision. As a result, prevention strategies in the form of vitamin supplementation should be increased for athletes.Clinical Relevance: These findings emphasize the clinical relevance of monitoring vitamin D levels in patients at risk for musculoskeletal injuries, and providing adequate care to those involved in high-demand physical activities.Strength of Recommendation: B.
本研究探讨维生素D缺乏与肱二头肌远端肌腱损伤之间的关联，结果表明，尽管维生素D缺乏与住院时间延长及各种肌肉骨骼问题相关，但其与肱二头肌远端肌腱损伤的联系尚不清楚。
维生素D缺乏与肱二头肌远端损伤风险升高相关，但与后续手术或翻修手术率增加无关。
病例对照研究。
3级。
利用PearlDiver数据（2011年1月1日至2018年10月31日）对336320例维生素D缺乏患者进行1:1匹配的回顾性比较研究。队列的平均年龄为55.7±13.2岁，进行多因素逻辑回归分析，以根据年龄和性别计算肱二头肌远端肌腱损伤和手术修复发生率，同时控制人口统计学和合并症因素。
维生素D缺乏患者肱二头肌远端肌腱病的1年发病率为每10万人年118例（95%可信区间），而匹配对照组为每10万人年44.3例。维生素D缺乏的男性患者在1年和2年后发生肱二头肌远端肌腱病的风险更高（校正比值比[aOR]=2.81，2.08 - 3.83；aOR = 2.80，2.21 - 3.56）。女性患者在这两年后风险也更高（aOR = 1.69，1.27 - 2.27；aOR = 1.57，1.26 - 1.96）。维生素D缺乏与手术修复或翻修手术风险升高无关。
在全国性队列研究中，维生素D缺乏诊断增加了肱二头肌远端肌腱病的风险，但未提高手术修复或翻修率。因此，应增加对运动员的维生素补充预防策略。临床相关性：这些发现强调了对有肌肉骨骼损伤风险的患者监测维生素D水平以及为从事高要求体育活动的人群提供充分护理的临床相关性。推荐强度：B级。
