Department of General Surgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Institute for Emergency and Disaster Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Nutr Clin Pract. 2024 Dec;39(6):1364-1374. doi: 10.1002/ncp.11202. Epub 2024 Aug 27.
The Global Leadership Initiative on Malnutrition (GLIM) criteria have rapidly developed into a principal methodological framework for nutrition diagnosis. However, the applicability of the GLIM criteria in patients with acute abdomen has not been validated.
This is a cross-sectional study conducted on patients diagnosed with acute abdomen and admitted to a tertiary hospital in southwest China. Nutrition risk screening was conducted using the Nutrition Risk Screening 2002, and patients identified with nutrition risk were assessed for malnutrition based on the GLIM criteria.
We enrolled a total of 440 patients with acute abdomen. The top three diagnoses of acute abdomen were intestinal obstruction (47.2%), acute appendicitis (23.1%), and digestive system perforation (8.8%). The prevalence of nutrition risk was 46.5%, with a malnutrition rate of 32.5% based on the GLIM. Patients with malnutrition according to the GLIM showed significantly higher rates of intensive care unit (ICU) admission (13.28% vs 7.07%; P = 0.003), increased hospitalization costs (median: 3315USD [interquartile range (IQR): 978-7852] vs 1641 [IQR: 816-3523] USD; P < 0.001), and longer length of hospital stay (LOS) (median: 8 [IQR: 5-13] vs 6 [IQR: 4-8] days; P < 0.001) compared with patients without malnutrition. Multivariate analysis indicated that GLIM-defined malnutrition was an independent predictor of hospitalization costs, and severe malnutrition was an independent predictor of ICU admission.
GLIM criteria are applicable for diagnosing malnutrition in patients with acute abdomen. The prevalence of malnutrition was high in patients with acute abdomen. Malnutrition was associated with increased ICU admission and LOS, along with higher economic burden.
全球营养不良领导倡议（GLIM）标准已迅速发展成为营养诊断的主要方法学框架。然而，GLIM 标准在急性腹痛患者中的适用性尚未得到验证。
这是一项在中国西南部一家三级医院就诊的急性腹痛患者的横断面研究。使用营养风险筛查 2002 进行营养风险筛查，对有营养风险的患者根据 GLIM 标准评估营养不良。
共纳入 440 例急性腹痛患者。急性腹痛的前三位诊断是肠梗阻（47.2%）、急性阑尾炎（23.1%）和消化系统穿孔（8.8%）。营养风险的患病率为 46.5%，根据 GLIM 标准，营养不良率为 32.5%。根据 GLIM 诊断为营养不良的患者入住重症监护病房（ICU）的比例明显更高（13.28%比 7.07%；P=0.003），住院费用更高（中位数：3315 美元[四分位距（IQR）：978-7852]比 1641 美元[IQR：816-3523]；P<0.001），住院时间更长（中位数：8[IQR：5-13]比 6[IQR：4-8]天；P<0.001）。多变量分析表明，GLIM 定义的营养不良是住院费用的独立预测因素，严重营养不良是 ICU 入住的独立预测因素。
GLIM 标准适用于诊断急性腹痛患者的营养不良。急性腹痛患者的营养不良患病率较高。营养不良与 ICU 入住和 LOS 增加以及更高的经济负担有关。
