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Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces in Cystic Fibrosis.

作者信息

Morgan Sarah J, Nichols David P, Ni Windy, Hong Gina, Salipante Stephen J, Solomon George M, Rowe Steven M, Clancy John P, Cramer Robert A, Singh Pradeep K

机构信息

Departments of Microbiology and Medicine, University of Washington, Seattle, Washington, USA.

Cystic Fibrosis Foundation, Bethesda, Maryland, USA.

出版信息

Am J Respir Crit Care Med. 2024 Nov 1;210(9):1155-1158. doi: 10.1164/rccm.202406-1128RL.

DOI:10.1164/rccm.202406-1128RL
PMID:39189854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12042367/
Abstract
摘要

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Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces in Cystic Fibrosis.依列卡福妥/替扎卡福妥/依伐卡托显著降低囊性纤维化患者的（相关指标，原文未明确具体所指）。
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Sci Rep. 2025 May 15;15(1):16906. doi: 10.1038/s41598-025-00187-z.
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Microbiology (Reading). 2025 Apr;171(4). doi: 10.1099/mic.0.001553.
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本文引用的文献

1
The cystic fibrosis treatment Trikafta affects the growth, viability, and cell wall of biofilms.囊性纤维化治疗药物 Trikafta 会影响生物膜的生长、存活和细胞壁。
mBio. 2023 Oct 31;14(5):e0151623. doi: 10.1128/mbio.01516-23. Epub 2023 Oct 13.
2
Infection, Allergy, and Inflammation: The Role of in Cystic Fibrosis.感染、过敏与炎症：[具体物质或因素]在囊性纤维化中的作用 。（原文中“in”后面的内容缺失）
Microorganisms. 2023 Aug 5;11(8):2013. doi: 10.3390/microorganisms11082013.
3
Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.依伐卡托/泰他卡托/艾美卡替三联复方制剂对囊性纤维化患者痰液黏弹性特性、气道感染和炎症的纵向影响。
Eur Respir J. 2023 Aug 3;62(2). doi: 10.1183/13993003.02153-2022. Print 2023 Aug.
4
Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist.药物改善 CFTR 功能可迅速降低痰中病原体密度，但肺部感染通常持续存在。
J Clin Invest. 2023 May 15;133(10):e167957. doi: 10.1172/JCI167957.
5
Advent of elexacaftor/tezacaftor/ivacaftor for cystic fibrosis treatment: What consequences on Aspergillus-related diseases? Preliminary insights.用于治疗囊性纤维化的依列卡福/替扎卡福/艾伐卡福的出现：对曲霉相关疾病有何影响？初步见解。
J Cyst Fibros. 2022 Nov;21(6):1084-1085. doi: 10.1016/j.jcf.2022.09.007. Epub 2022 Sep 21.
6
in the cystic fibrosis lung: pros and cons of azole therapy.在囊性纤维化肺部：唑类疗法的利弊
Infect Drug Resist. 2016 Sep 20;9:229-238. doi: 10.2147/IDR.S63621. eCollection 2016.
7
Fungal epidemiology and diversity in cystic fibrosis patients over a 5-year period in a national reference center.在一家国家参考中心，对囊性纤维化患者5年期间的真菌流行病学及多样性研究
Med Mycol. 2016 Nov 1;54(8):781-6. doi: 10.1093/mmy/myw035. Epub 2016 Jun 30.
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Rapid and specific detection of section Fumigati and Aspergillus fumigatus in human samples using a new multiplex real-time PCR.使用新型多重实时聚合酶链反应快速、特异性检测人体样本中的烟曲霉组和烟曲霉
Diagn Microbiol Infect Dis. 2014 Oct;80(2):111-8. doi: 10.1016/j.diagmicrobio.2014.06.003. Epub 2014 Jun 19.