Department of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, New York, New York.
Robert Stempel College of Public Health and Social Work, Florida International University, Miami, Florida.
AIDS Educ Prev. 2024 Aug;36(4):272-284. doi: 10.1521/aeap.2024.36.4.272.
Our study assessed the association between methamphetamine (i.e., crystal meth, CM) use and awareness and interest in event-driven (ED) PrEP among HIV-negative and those with unknown serostatus cisgender males and transgender people. We performed log-binomial regression analysis to predict awareness (i.e., having heard of ED PrEP) and being interested in ED PrEP. We found that participants who recently used CM were less likely to know of ED PrEP (aPR = 0.83, 95% CI [0.69, 0.99]) but more interested in ED PrEP (aPR = 1.12, 95% CI [1.01, 1.30]), after accounting for demographic and HIV-related behaviors. Opportunities to expand PrEP uptake and improve adherence among individuals who report CM use are essential to impact the HIV epidemic significantly. Continued research on the needs and best practices to work with this community is needed to ensure a successful rollout and implementation of ED PrEP.
我们的研究评估了冰毒（即晶体冰，CM）使用与 HIV 阴性和未知血清学状态的顺性别男性和跨性别者对事件驱动（ED）PrEP 的认知和兴趣之间的关联。我们进行了对数二项式回归分析，以预测对 ED PrEP 的认知（即听说过 ED PrEP）和对 ED PrEP 的兴趣。我们发现，最近使用 CM 的参与者不太可能了解 ED PrEP（调整后的比值比[aPR] = 0.83，95%置信区间[0.69, 0.99]），但对 ED PrEP 更感兴趣（aPR = 1.12，95%置信区间[1.01, 1.30]），这在考虑了人口统计学和与 HIV 相关的行为之后。对于那些报告使用 CM 的人，扩大 PrEP 使用率和提高依从性的机会对于显著影响 HIV 流行至关重要。需要继续研究满足该群体需求和最佳实践的方法，以确保 ED PrEP 的成功推出和实施。
