Personalised Oncology Division, Walter and Eliza Hall Institute, Melbourne, Victoria, Australia.
Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
JNCI Cancer Spectr. 2024 Sep 2;8(5). doi: 10.1093/jncics/pkae073.
Quality indicators are essential for measuring and benchmarking the quality of cancer care. Although there are well-established metrics for early-stage colorectal cancer (CRC), few exist for advanced CRC. This scoping review aimed to collate and review all quality indicators for metastatic CRC.
A dedicated search was performed of Web of Science, PubMed, CINAHL, and relevant gray literature to identify quality indicators for metastatic CRC, evaluating the diagnostic workup, systemic anticancer treatments, surgical approaches, radiation approaches, supportive care, and palliative or terminal care provided to patients.
We identified 11 articles, of which 5 were systematized reviews and 6 concerned the development, validation, or operationalization of quality indicators. Thirty-five distinct quality indicators for metastatic CRC were extracted across 6 domains of care: 1) diagnosis, staging, and treatment planning; 2) systemic anticancer treatment; 3) radiation oncology; 4) surgical approaches; 5) supportive care; and 6) palliative and end-of-life care, with a general quality indicator of overall survival. Of the 35 quality indicators extracted, 8 (23%) were unique to metastatic CRC and 27 (77%) were generic quality indicators across different tumor types but applicable to metastatic CRC.
There are few quality indicators specifically relevant to metastatic CRC. Those that do exist are generally generic process measures used across tumor types and do not measure the nuance or complexity of current multidisciplinary treatment of patients with metastatic CRC.
质量指标对于衡量和基准化癌症治疗质量至关重要。虽然早期结直肠癌（CRC）有成熟的指标，但晚期 CRC 的指标却很少。本范围综述旨在收集和审查转移性 CRC 的所有质量指标。
专门在 Web of Science、PubMed、CINAHL 和相关灰色文献中进行了搜索，以确定转移性 CRC 的质量指标，评估诊断工作、系统抗癌治疗、手术方法、放射治疗方法、支持性护理以及为患者提供的姑息或终末期护理。
我们确定了 11 篇文章，其中 5 篇是系统评价，6 篇涉及质量指标的开发、验证或实施。在 6 个护理领域中提取了 35 个转移性 CRC 的独特质量指标：1）诊断、分期和治疗计划；2）系统抗癌治疗；3）放射肿瘤学；4）手术方法；5）支持性护理；6）姑息和临终关怀，总体生存率是一般质量指标。在提取的 35 个质量指标中，8 个（23%）是转移性 CRC 特有的，27 个（77%）是不同肿瘤类型通用的质量指标，但适用于转移性 CRC。
很少有专门针对转移性 CRC 的质量指标。现有的这些指标通常是跨肿瘤类型使用的通用过程指标，无法衡量当前多学科治疗转移性 CRC 患者的细微差别或复杂性。
