Drugs of addiction and stroke: diagnostic and treatment challenges in the emergency department.

Drugs of addiction have been associated with an increased risk of both hemorrhagic and ischemic stroke. While the mechanisms that increase stroke risk are well recognized for the most commonly used substances, there is limited evidence to guide the management and treatment of stroke in the setting of concurrent substance use disorder. This review presents a comprehensive approach to evaluation and management of stroke in patients with substance use disorders. Identification of concurrent drug intoxication and guidelines for drug screening in stroke patients are discussed, along with standardized treatment strategies to improve care and outcomes in these patients.