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神经形状完成用于个性化颌面外科手术。

Neural shape completion for personalized Maxillofacial surgery.

机构信息

eDIMES Lab - Laboratory of Bioengineering, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Department of Computer Science and Engineering (DISI), University of Bologna, Bologna, Italy.

出版信息

Sci Rep. 2024 Aug 27;14(1):19810. doi: 10.1038/s41598-024-68084-5.

DOI:10.1038/s41598-024-68084-5
PMID:39191797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11350194/
Abstract

In this paper, we investigate the effectiveness of shape completion neural networks as clinical aids in maxillofacial surgery planning. We present a pipeline to apply shape completion networks to automatically reconstruct complete eumorphic 3D meshes starting from a partial input mesh, easily obtained from CT data routinely acquired for surgery planning. Most of the existing works introduced solutions to aid the design of implants for cranioplasty, i.e. all the defects are located in the neurocranium. In this work, we focus on reconstructing defects localized on both neurocranium and splanchnocranium. To this end, we introduce a new dataset, specifically designed for this task, derived from publicly available CT scans and subjected to a comprehensive pre-processing procedure. All the scans in the dataset have been manually cleaned and aligned to a common reference system. In addition, we devised a pre-processing stage to automatically extract point clouds from the scans and enrich them with virtual defects. We experimentally compare several state-of-the-art point cloud completion networks and identify the two most promising models. Finally, expert surgeons evaluated the best-performing network on a clinical case. Our results show how casting the creation of personalized implants as a problem of shape completion is a promising approach for automatizing this complex task.

摘要

在本文中,我们研究了形状完成神经网络作为颌面外科手术规划临床辅助的有效性。我们提出了一种应用形状完成网络的流程,从手术计划中常规获取的 CT 数据中容易获得的部分输入网格开始,自动重建完整的正形 3D 网格。现有的大多数工作都提出了辅助颅骨成形术设计植入物的解决方案,即所有的缺陷都位于颅盖骨中。在这项工作中,我们专注于重建位于颅盖骨和颅底骨上的缺陷。为此,我们引入了一个新的数据集,该数据集专门为此任务设计,源自公开的 CT 扫描,并经过了全面的预处理过程。数据集中的所有扫描都经过了手动清理并对齐到一个共同的参考系统。此外,我们设计了一个预处理阶段,可以从扫描中自动提取点云,并使用虚拟缺陷对其进行丰富。我们在实验中比较了几种最先进的点云完成网络,并确定了两个最有前途的模型。最后,专家外科医生对临床病例中表现最佳的网络进行了评估。我们的结果表明,将个性化植入物的创建视为形状完成问题是自动化这一复杂任务的一种很有前途的方法。

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引用本文的文献

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Bioengineering (Basel). 2025 May 8;12(5):498. doi: 10.3390/bioengineering12050498.

本文引用的文献

1
Deep learning-based framework for automatic cranial defect reconstruction and implant modeling.基于深度学习的颅骨缺损自动重建和植入物建模框架。
Comput Methods Programs Biomed. 2022 Nov;226:107173. doi: 10.1016/j.cmpb.2022.107173. Epub 2022 Oct 11.
2
CranGAN: Adversarial Point Cloud Reconstruction for patient-specific Cranial Implant Design.CranGAN:用于患者特定颅面植入物设计的对抗式点云重建。
Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:603-608. doi: 10.1109/EMBC48229.2022.9871069.
3
Virtual reconstruction of midfacial bone defect based on generative adversarial network.
基于生成对抗网络的中面部骨缺损的虚拟重建。
Head Face Med. 2022 Jun 27;18(1):19. doi: 10.1186/s13005-022-00325-2.
4
PMP-Net++: Point Cloud Completion by Transformer-Enhanced Multi-Step Point Moving Paths.PMP-Net++:基于Transformer增强多步点移动路径的点云补全
IEEE Trans Pattern Anal Mach Intell. 2023 Jan;45(1):852-867. doi: 10.1109/TPAMI.2022.3159003. Epub 2022 Dec 5.
5
Three-dimensional deep learning to automatically generate cranial implant geometry.三维深度学习自动生成颅骨植入物几何形状。
Sci Rep. 2022 Feb 17;12(1):2683. doi: 10.1038/s41598-022-06606-9.
6
Deep learning for cranioplasty in clinical practice: Going from synthetic to real patient data.深度学习在临床实践中的颅骨修补术:从合成到真实患者数据。
Comput Biol Med. 2021 Oct;137:104766. doi: 10.1016/j.compbiomed.2021.104766. Epub 2021 Aug 14.
7
Automatic skull defect restoration and cranial implant generation for cranioplasty.颅骨修复术的自动颅骨缺损修复和颅骨植入物生成。
Med Image Anal. 2021 Oct;73:102171. doi: 10.1016/j.media.2021.102171. Epub 2021 Jul 20.
8
Skull shape reconstruction using cascaded convolutional networks.使用级联卷积网络进行颅骨形状重建。
Comput Biol Med. 2020 Aug;123:103886. doi: 10.1016/j.compbiomed.2020.103886. Epub 2020 Jun 27.
9
Virtual reconstruction of bilateral midfacial defects by using statistical shape modeling.利用统计形状建模对双侧面中部缺损进行虚拟重建。
J Craniomaxillofac Surg. 2019 Jul;47(7):1054-1059. doi: 10.1016/j.jcms.2019.03.027. Epub 2019 Apr 1.
10
Surgery of complex craniofacial defects: A single-step AM-based methodology.基于增材制造的复杂颅面缺损的单次手术治疗方法。
Comput Methods Programs Biomed. 2018 Oct;165:225-233. doi: 10.1016/j.cmpb.2018.09.002. Epub 2018 Sep 5.