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[新生儿科中二氧化碳分压对脑血流的意义。一项多普勒超声研究]

[Significance of pCO2 for cerebral blood flow in neonatology. A Doppler sonographic study].

作者信息

Jorch G, Menge U

出版信息

Monatsschr Kinderheilkd. 1985 Jan;133(1):38-42.

PMID:3919282
Abstract

Range-gated pulsed Doppler-ultrasonographic blood flow measurements of 3 cerebral arteries (a. cerebri anterior, a. carotis interna, a. basilaris) were performed during acute pCO2-changes in 16 neonates treated in an intensive care unit. Pulsatility index, peak systolic and end diastolic flow velocity, and mean velocity were evaluated. Mean velocity in the a. carotis interna and the a. basilaris depends on the pCO2, and increases resp. decreases by 5.6% per mm Hg of rise resp. fall of the pCO2. Assuming no pCO2-dependent diameter changes of the large cerebral arteries volume flow would increase resp. decrease by a proportional amount. When obtaining qualitative or semiquantitative informations about volume flow by Doppler-ultrasonography anatomic conditions must be considered carefully.

摘要

在重症监护病房接受治疗的16例新生儿急性二氧化碳分压(pCO2)变化期间,对3条脑动脉(大脑前动脉、颈内动脉、基底动脉)进行了距离选通脉冲多普勒超声血流测量。评估了搏动指数、收缩期峰值和舒张末期血流速度以及平均速度。颈内动脉和基底动脉的平均速度取决于pCO2,且随着pCO2每升高或降低1 mmHg分别增加或降低5.6%。假设大脑大动脉的直径不随pCO2变化,那么容积流量将相应增加或减少。当通过多普勒超声获取有关容积流量的定性或半定量信息时,必须仔细考虑解剖条件。

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Monatsschr Kinderheilkd. 1985 Jan;133(1):38-42.
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引用本文的文献

1
Cerebral blood flow velocities in the first minutes of life.出生后最初几分钟的脑血流速度。
Eur J Pediatr. 1993 Mar;152(3):269-70. doi: 10.1007/BF01956162.
2
Failure of autoregulation of cerebral blood flow in neonates studied by pulsed Doppler ultrasound of the internal carotid artery.通过颈内动脉脉冲多普勒超声研究新生儿脑血流自动调节功能障碍。
Eur J Pediatr. 1987 Sep;146(5):468-72. doi: 10.1007/BF00441596.
3
Cerebral blood flow in newborn infants with and without mechanical ventilation.有或无机械通气的新生儿的脑血流
Pediatr Radiol. 1989;19(8):509-12. doi: 10.1007/BF02389558.