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运动对2型糖尿病影响的潜在机制:研究进展综述

Mechanism underlying the effects of exercise against type 2 diabetes: A review on research progress.

作者信息

Peng Chen-Jian, Chen Shuo, Yan Su-Ying, Zhao Jian-Ning, Luo Zhi-Wen, Qian Yuan, Zhao Guo-Liang

机构信息

Department of Sports Medicine, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing 210022, Jiangsu Province, China.

Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.

出版信息

World J Diabetes. 2024 Aug 15;15(8):1704-1711. doi: 10.4239/wjd.v15.i8.1704.

DOI:10.4239/wjd.v15.i8.1704
PMID:39192863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346101/
Abstract

Exercise has emerged as one of the important and effective non-drug therapies used for management of type 2 diabetes (T2D) in certain nations. The present report summarizes the latest findings from the research on the beneficial effect of exercise on T2D. The objectives were to provide references for the theoretical study and the clinical practice of exercise-based management of T2D, in addition to identify the limitations of the existing literature, thereby provide direction for future research in this field.

摘要

在某些国家,运动已成为用于管理2型糖尿病(T2D)的重要且有效的非药物疗法之一。本报告总结了运动对T2D有益作用的最新研究结果。目的是为基于运动的T2D管理的理论研究和临床实践提供参考,此外还旨在识别现有文献的局限性,从而为该领域的未来研究指明方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/0d3b577f54cb/WJD-15-1704-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/d20a2782db21/WJD-15-1704-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/496d6826c6d2/WJD-15-1704-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/0d3b577f54cb/WJD-15-1704-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/d20a2782db21/WJD-15-1704-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/496d6826c6d2/WJD-15-1704-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc90/11346101/0d3b577f54cb/WJD-15-1704-g003.jpg

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本文引用的文献

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Nat Commun. 2024 May 15;15(1):3690. doi: 10.1038/s41467-024-47843-y.
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Exercise-Induced Reduction of IGF1R Sumoylation Attenuates Neuroinflammation in APP/PS1 Transgenic Mice.运动诱导的IGF1R SUMO化减少减轻了APP/PS1转基因小鼠的神经炎症。
J Adv Res. 2025 Mar;69:279-297. doi: 10.1016/j.jare.2024.03.025. Epub 2024 Mar 31.
3
Gut Microbiota and Blood Metabolites Related to Fiber Intake and Type 2 Diabetes.
膳食纤维摄入与 2 型糖尿病相关的肠道微生物群和血液代谢物。
Circ Res. 2024 Mar 29;134(7):842-854. doi: 10.1161/CIRCRESAHA.123.323634. Epub 2024 Mar 28.
4
High-Intensity Interval Versus Moderate-Intensity Continuous Exercise Training on Glycemic Control, Beta Cell Function, and Aerobic Fitness in Women with Type 2 Diabetes.高强度间歇训练与中等强度持续训练对 2 型糖尿病女性血糖控制、胰岛β细胞功能和有氧适能的影响。
Biol Res Nurs. 2024 Jul;26(3):449-459. doi: 10.1177/10998004241239330. Epub 2024 Mar 13.
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Diabetes Care. 2024 Feb 1;47(2):295-303. doi: 10.2337/dc23-0800.
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9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2024.9. 血糖治疗的药物学方法:2024 年糖尿病护理标准。
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