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安德森-海因斯肾盂成形术治疗单肾新生儿肾盂输尿管连接部综合征:一例报告

Pyeloureteral Junction Syndrome in a Neonate With a Solitary Kidney Treated by Anderson-Hynes Pyeloplasty: A Case Report.

作者信息

Benomar Ismail, Qarouach Souha, Rami Mohamed, Belkacem Rachid, Bouhafs Mohamed Amine

机构信息

Pediatric Surgery, Children's Hospital Faculty of Medicine and Pharmacy, University Mohamed V, Rabat, MAR.

出版信息

Cureus. 2024 Jul 28;16(7):e65589. doi: 10.7759/cureus.65589. eCollection 2024 Jul.

DOI:10.7759/cureus.65589
PMID:39192924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11349144/
Abstract

A rare disorder called newborn hydronephrosis is mostly caused by the obstruction of the pyeloureteral junction. We describe a case study of a male neonate who underwent Anderson-Hynes pyeloplasty to effectively cure hydronephrosis in a single kidney that was further complicated by early renal failure. Considering kidney failure can result in progressive renal fibrosis, early management is essential. The gold standard is Anderson-Hynes pyeloplasty, which is usually advised for individuals who weigh over 10 kg. Percutaneous nephrostomy is frequently used in the early stages of care for newborns in order to reduce dilatation and restore renal elasticity. After surgery, the resolution of hydronephrosis may take up to 24 months. We note that pyeloureteral junction obstruction can appear as a single anomaly or a component of a multifactorial illness. This study aims to contribute to the discourse surrounding the optimal timing of Anderson-Hynes pyeloplasty in pediatric patients, providing insights into clinical management strategies and outcomes.

摘要

一种名为新生儿肾积水的罕见病症主要由肾盂输尿管连接处梗阻引起。我们描述了一例男性新生儿的病例研究,该新生儿接受了安德森-海因斯肾盂成形术,以有效治愈单肾肾积水,且该肾积水因早期肾衰竭而进一步复杂化。考虑到肾衰竭会导致进行性肾纤维化,早期治疗至关重要。金标准是安德森-海因斯肾盂成形术,通常建议用于体重超过10公斤的个体。经皮肾造瘘术在新生儿护理早期经常使用,以减轻扩张并恢复肾脏弹性。手术后,肾积水的消退可能需要长达24个月。我们注意到肾盂输尿管连接处梗阻可能表现为单一异常或多因素疾病的一个组成部分。本研究旨在为围绕儿科患者安德森-海因斯肾盂成形术最佳时机的讨论做出贡献,提供有关临床管理策略和结果的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/c5c37e44fa42/cureus-0016-00000065589-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/619890a3e031/cureus-0016-00000065589-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/fc8d26eb552c/cureus-0016-00000065589-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/c5c37e44fa42/cureus-0016-00000065589-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/619890a3e031/cureus-0016-00000065589-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/fc8d26eb552c/cureus-0016-00000065589-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7e3/11349144/c5c37e44fa42/cureus-0016-00000065589-i03.jpg

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1
Giant Bilateral Hydronephrosis in A Newborn-A Case Report.新生儿双侧巨大肾积水——病例报告
Children (Basel). 2022 Dec 2;9(12):1890. doi: 10.3390/children9121890.
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Resolution of hydronephrosis after pyeloplasty in children.儿童肾盂成形术后肾积水的消退
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Clinical, surgical and morphological assessment of the pyeloureteral syndrome.肾盂输尿管综合征的临床、手术及形态学评估
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Hydronephrosis After Pyeloplasty: "Will It Go Away?".肾盂成形术后肾积水:“它会消失吗?”
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Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery.在泌尿道间充质中,钙调神经磷酸酶是肾盂输尿管蠕动机制发育所必需的。
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