Felix Bryan, Aldoohan Fawaz, Kadirage Hansanee U, Keelathara Sajeev Sethulakshmi, Kayani Maryam, Hag Saeed Mohamed Abdelsalam Ibrahim, Vempatapu Sruthi, Nasim Khadija, Pendem Harini, Armenta Annia P, Nazir Zahra
Medical Student, Avalon University School of Medicine, Los Angeles, USA.
Internal Medicine, American Academy of Research and Academics, Delaware, USA.
Cureus. 2024 Jul 28;16(7):e65568. doi: 10.7759/cureus.65568. eCollection 2024 Jul.
Non-ST-segment elevation myocardial infarction (NSTEMI) is associated with significant morbidity and mortality, occurring when the heart's need for oxygen cannot be met. It is defined by elevated cardiac biomarkers without ST-segment elevation and often carries a poorer prognosis than most ST-segment elevation events. NSTEMI usually results from severe coronary artery narrowing, transient occlusion, or microembolization of thrombus/atheromatous material. Patients with NSTEMI often have multiple comorbidities, which can worsen their prognosis and complicate treatment. This study aims to investigate the impact of comorbidities such as hypertension (HTN), diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), obesity, dyslipidemia, and smoking on patients with NSTEMI. The prevalence of each comorbidity is examined individually within the NSTEMI population to provide a clearer picture of how frequently these conditions co-occur with NSTEMI and how they affect the established NSTEMI treatment protocols. This paper sheds light on the interaction between NSTEMI and commonly associated comorbidities through a comprehensive literature review and data analysis. This is critical for optimizing clinical decision-making and enhancing patient care, ultimately improving outcomes in this high-risk patient population.
非ST段抬高型心肌梗死（NSTEMI）与显著的发病率和死亡率相关，当心脏的氧气需求无法得到满足时就会发生。它由心肌生物标志物升高且无ST段抬高来定义，其预后通常比大多数ST段抬高事件更差。NSTEMI通常由严重冠状动脉狭窄、短暂闭塞或血栓/动脉粥样硬化物质的微栓塞引起。NSTEMI患者常伴有多种合并症，这会使他们的预后恶化并使治疗复杂化。本研究旨在调查高血压（HTN）、糖尿病（DM）、慢性阻塞性肺疾病（COPD）、肥胖、血脂异常和吸烟等合并症对NSTEMI患者的影响。在NSTEMI人群中分别检查每种合并症的患病率，以便更清楚地了解这些病症与NSTEMI同时出现的频率以及它们如何影响既定的NSTEMI治疗方案。本文通过全面的文献综述和数据分析，揭示了NSTEMI与常见相关合并症之间的相互作用。这对于优化临床决策和加强患者护理至关重要，最终改善这一高危患者群体的治疗结果。
