Chadha Nikita, Sterling Richard K
Department of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University Health System, Richmond, Virginia.
Gastroenterol Hepatol (N Y). 2024 Aug;20(6):322-329.
Identifying hepatic fibrosis is paramount in managing patients with chronic liver disease. The etiology of liver disease can be owing to many factors, including chronic viral hepatitis, steatotic liver diseases such as alcohol-associated liver disease or metabolic dysfunction-associated steatotic liver disease, autoimmune hepatitis, and cholestatic liver diseases. Currently, invasive liver biopsy with histopathologic evaluation is the gold standard; however, noninvasive tests are becoming more prevalent, especially because they do not carry the risks of invasive procedures such as biopsy. This article reviews noninvasive tests for fibrosis, separating them into blood-based and imaging-based tests.
识别肝纤维化对于慢性肝病患者的管理至关重要。肝病的病因可能归因于多种因素，包括慢性病毒性肝炎、脂肪性肝病，如酒精性肝病或代谢功能障碍相关脂肪性肝病、自身免疫性肝炎以及胆汁淤积性肝病。目前，经组织病理学评估的侵入性肝活检是金标准；然而，非侵入性检测正变得越来越普遍，特别是因为它们不存在诸如活检等侵入性操作的风险。本文综述了用于纤维化的非侵入性检测，将其分为基于血液的检测和基于成像的检测。
