Can Beril, Piskun Victoria, Dunn Abby, Cartwright-Hatton Sam
School of Psychology, University of Sussex, Falmer, Brighton, United Kingdom.
School of Psychology, University of Surrey, Guilford, Surrey, United Kingdom.
Front Psychiatry. 2024 Aug 13;15:1425519. doi: 10.3389/fpsyt.2024.1425519. eCollection 2024.
Parental psychosis (bipolar disorder and schizophrenia) are major risk factors for mental health problems in offspring. Although interventions that focus on parenting and the family environment have shown effectiveness in mitigating this risk, no systematic review has examined the impact of simply treating adult bipolar disorder or schizophrenia on their dependent children's outcomes.
To systematically review the effects (in randomized controlled trials) of adult-based interventions for bipolar disorder and schizophrenia, on offspring mental health and wellbeing.
Eligibility criteria included randomized controlled trials that examined the treatment of adults with bipolar disorder and schizophrenia that also included child mental health and wellbeing outcomes. PubMed, Scopus, PsycINFO, and PsychArticles databases were searched.
168,317 studies were reviewed; however, zero studies that met the inclusion criteria could be found.
The existing research aimed at treating adult bipolar disorder and schizophrenia has so far overlooked the potential advantages that these treatments could provide for their offspring. This is a missed opportunity to understand the mechanisms of intergenerational transmission. Researchers examining treatments for adults with bipolar disorder and schizophrenia should, where appropriate, consider including both adult and child mental health outcomes in their trials.
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=431007, identifier CRD42023431007.
父母患有精神病（双相情感障碍和精神分裂症）是子女出现心理健康问题的主要风险因素。尽管专注于养育方式和家庭环境的干预措施已显示出在减轻这种风险方面的有效性，但尚无系统评价研究单纯治疗成人双相情感障碍或精神分裂症对其受抚养子女结局的影响。
系统评价针对双相情感障碍和精神分裂症的基于成人的干预措施（在随机对照试验中）对子女心理健康和幸福的影响。
纳入标准包括检查双相情感障碍和精神分裂症成人治疗情况且包含儿童心理健康和幸福结局的随机对照试验。检索了PubMed、Scopus、PsycINFO和PsychArticles数据库。
共检索了168,317项研究；然而，未找到符合纳入标准的研究。
目前旨在治疗成人双相情感障碍和精神分裂症的研究忽略了这些治疗可能为其子女带来的潜在益处。这是一个了解代际传播机制的错失机会。研究双相情感障碍和精神分裂症成人治疗方法的研究人员应在适当情况下考虑在试验中纳入成人和儿童心理健康结局。
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=431007，标识符CRD42023431007。
