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探索富血小板血浆疗法治疗膝骨关节炎:深入分析

Exploring Platelet-Rich Plasma Therapy for Knee Osteoarthritis: An In-Depth Analysis.

作者信息

Blaga Florin Nicolae, Nutiu Alexandru Stefan, Lupsa Alex Octavian, Ghiurau Nicu Adrian, Vlad Silviu Valentin, Ghitea Timea Claudia

机构信息

County Clinical Emergency Hospital of Oradea, 65 Gheorghe Doja Street, 410169 Oradea, Romania.

Department of Surgical Specialties, Faculty of Medicine and Pharmacy, University of Oradea, 10 1st Decembrie Street, 410073 Oradea, Romania.

出版信息

J Funct Biomater. 2024 Aug 9;15(8):221. doi: 10.3390/jfb15080221.

DOI:10.3390/jfb15080221
PMID:39194659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11355339/
Abstract

The use of platelet-rich plasma (PRP) in all medical fields is currently gaining popularity (1). PRP is a biological product that can be defined as a segment of the plasma fraction of autologous blood with a platelet concentration level above the baseline (2). The fact that it has uses in tissue regeneration and wound healing has caught the eye of orthopedic surgeons as well, as intra-articular treatments have continued to evolve. Its benefits in the treatment of different osteoarticular pathologies are of great interest in the evolving orthopedic community, targeting mostly knee osteoarthritis, meniscus and ligament injuries (3). The purpose of this review is to update the reader on the current uses of platelet-rich plasma (PRP) in the treatment of knee osteoarthritis pathology and to provide clinical feedback on its uses in the fields of orthopedic and sports medicine practice (4). We proceeded in studying 180 titles and abstracts eligible for inclusion. Compared to alternative treatments, PRP injections greatly improve the function of the knee joint.

摘要

富血小板血浆(PRP)在所有医学领域的应用目前正日益普及(1)。PRP是一种生物制品,可定义为自体血液血浆部分中血小板浓度高于基线水平的部分(2)。它在组织再生和伤口愈合方面的应用也引起了骨科医生的关注,因为关节内治疗一直在不断发展。其在治疗不同骨关节炎病理方面的益处,在不断发展的骨科领域引起了极大兴趣,主要针对膝关节骨关节炎、半月板和韧带损伤(3)。本综述的目的是向读者介绍富血小板血浆(PRP)目前在治疗膝关节骨关节炎病理方面的应用,并提供其在骨科和运动医学实践领域应用的临床反馈(4)。我们对180篇符合纳入标准的标题和摘要进行了研究。与其他治疗方法相比,PRP注射能显著改善膝关节功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/512fe0aee88b/jfb-15-00221-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/cde3a5e79c2c/jfb-15-00221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/a903e12976f0/jfb-15-00221-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/1080adb8aead/jfb-15-00221-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/512fe0aee88b/jfb-15-00221-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/cde3a5e79c2c/jfb-15-00221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/a903e12976f0/jfb-15-00221-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/1080adb8aead/jfb-15-00221-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a318/11355339/512fe0aee88b/jfb-15-00221-g004.jpg

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Advancements in tissue engineering for articular cartilage regeneration.用于关节软骨再生的组织工程学进展。
Heliyon. 2024 Feb 1;10(3):e25400. doi: 10.1016/j.heliyon.2024.e25400. eCollection 2024 Feb 15.
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Platelet-Rich Plasma Therapy: An Effective Approach for Managing Knee Osteoarthritis.
J Clin Med. 2025 Mar 16;14(6):2020. doi: 10.3390/jcm14062020.
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Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a systematic review and network meta-analysis.不同剂量富血小板血浆注射治疗膝骨关节炎的疗效比较:一项系统评价和网状Meta分析
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Evaluating the Efficacy of Platelet-Rich Plasma in Treating Primary Knee Osteoarthritis: A Prospective Interventional Study.评估富血小板血浆治疗原发性膝关节骨关节炎的疗效:一项前瞻性干预研究。
Cureus. 2024 Oct 14;16(10):e71415. doi: 10.7759/cureus.71415. eCollection 2024 Oct.
富血小板血浆疗法:一种治疗膝关节骨关节炎的有效方法。
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