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接受多次CT检查且累积有效剂量超过100毫希沃特的患者的发病和死亡归因风险。

Incidence and Mortality Life-Attributable Risks for Patients Subjected to Recurrent CT Examinations and Cumulative Effective Dose Exceeding 100 mSv.

作者信息

Z Dalah Entesar, B Mohamed Ahmed, M Al Bastaki Usama, A Khan Sabaa

机构信息

HQ Diagnostic Imaging Department, Dubai Health, Dubai, United Arab Emirates.

College of Medicine, Mohammed Bin Rashid University, Dubai Health, Dubai, United Arab Emirates.

出版信息

Clin Pract. 2024 Aug 10;14(4):1550-1561. doi: 10.3390/clinpract14040125.

DOI:10.3390/clinpract14040125
PMID:39194929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11353021/
Abstract

Computed tomography (CT) multi-detector array has been heavily utilized over the past decade. While transforming an individual's diagnosis, the risk of developing pathogenesis as a result remains a concern. The main aim of this institutional cumulative effective dose (CED) review is to highlight the number of adult individuals with a record of CED ≥ 100 mSv over a time span of 5 years. Further, we aim to roughly estimate both incidence and mortality life-attributable risks (LARs) for the shortlisted individuals. CT studies performed over one year, in one dedicated trauma and emergency facility, were retrospectively retrieved and analyzed. Individuals with historical radiological CED ≥ 100 mSv were short-listed. LARs were defined and established based on organ, age and gender. Out of the 4406 CT studies reviewed, 22 individuals were found with CED ≥ 100 mSv. CED varied amongst the short-listed individuals, with the highest CED registered being 223.0 mSv, for a 57-year-old male, cumulated over an average study interval of 46.3 days. The highest median mortality risk was for females, 214 per 100,000 registered for the age group 51-60 years. While certain clinical indications and diseases require close follow-up using radiological examinations, the benefit-to-risk ratio should be carefully considered, particularly when CT is requested.

摘要

在过去十年中,计算机断层扫描(CT)多探测器阵列得到了广泛应用。虽然它改变了个体的诊断方式,但由此引发发病机制的风险仍然令人担忧。本机构累积有效剂量(CED)审查的主要目的是突出在5年时间跨度内记录的CED≥100 mSv的成年个体数量。此外,我们旨在大致估计入围个体的发病率和归因于寿命的死亡风险(LARs)。回顾性检索并分析了在一个专门的创伤和急救设施中进行的为期一年的CT研究。将历史放射学CED≥100 mSv的个体列入入围名单。根据器官、年龄和性别定义并确定LARs。在审查的4406项CT研究中,发现22名个体的CED≥100 mSv。入围个体的CED各不相同,记录的最高CED为223.0 mSv,是一名57岁男性,在平均46.3天的研究间隔内累积。女性的中位死亡风险最高,51 - 60岁年龄组每10万人中有214人。虽然某些临床指征和疾病需要使用放射学检查进行密切随访,但应仔细考虑风险效益比,尤其是在要求进行CT检查时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2be/11353021/bb37a928eac5/clinpract-14-00125-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2be/11353021/bb37a928eac5/clinpract-14-00125-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2be/11353021/bb37a928eac5/clinpract-14-00125-g001.jpg

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不同基于蒙特卡罗模拟的软件方法在婴儿 CT 中估算器官和有效剂量的比较,并与直接体模测量进行比较。
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