Silber T J, D'Angelo L
Am J Dis Child. 1985 Apr;139(4):335-7. doi: 10.1001/archpedi.1985.02140060017014.
Psychosis and/or seizures following the administration of intramuscular penicillin G procaine have not been reported in the pediatric literature to our knowledge. This omission is regrettable in light of the frequency with which this treatment is indicated as therapy for gonococcal infections. We report clinical data from four patients afflicted by this reaction known as Hoigne's syndrome. The dramatic and unexpected manifestation of this condition calls for an immediate diagnosis to proceed with the appropriate treatment.
据我们所知，儿科文献中尚未报道过肌肉注射普鲁卡因青霉素G后出现精神病和/或癫痫发作的情况。鉴于这种治疗方法常用于淋病感染的治疗，这种遗漏令人遗憾。我们报告了4例患有这种被称为霍伊涅综合征反应的患者的临床数据。这种疾病的显著且意外的表现需要立即诊断以便进行适当的治疗。
