Domoto K, Ben R, Wei J Y, Pass T M, Komaroff A L
Am J Public Health. 1985 Mar;75(3):243-5. doi: 10.2105/ajph.75.3.243.
We examined the yield of a battery of 19 screening laboratory tests performed routinely in 70 functionally intact patients, averaging 82.6 years of age and residing at a chronic care facility. The 70 patients underwent 3,903 screening tests (70 admission batteries and 156 batteries at annual intervals). Twenty per cent of the admission test results and 17 per cent of all subsequent annual test results were "abnormal". "New abnormal" results (previously unknown to the responsible physicians) occurred primarily in five of the 19 screening tests; they were found in 13 per cent of all admission screening tests and in 6 per cent of all annual tests. However, many of the "new abnormalities" were only minimally outside the normal range, and only 26 (0.7 per cent) led to further diagnostic evaluation. Of these 26, only four (0.1 per cent of all tests ordered) led to changes in patient management, none of which benefited the patient in an important way.
我们对70名功能健全的患者进行了一系列19项常规筛查实验室检测,这些患者平均年龄82.6岁,居住在一家慢性病护理机构。这70名患者接受了3903次筛查检测(70次入院时的全套检测以及每年156次全套检测)。入院检测结果的20%以及所有后续年度检测结果的17%为“异常”。“新出现的异常”结果(负责医生之前未知)主要出现在19项筛查检测中的5项;在所有入院筛查检测中有13%出现此类结果,在所有年度检测中有6%出现此类结果。然而,许多“新出现的异常”仅略超出正常范围,只有26项(0.7%)导致进一步的诊断评估。在这26项中,只有4项(所开所有检测的0.1%)导致了患者管理的改变,但没有一项对患者有重大益处。