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21 年饮食轨迹与挪威老年人虚弱:1994-2016 年特罗姆瑟研究。

Dietary trajectories over 21 years and frailty in Norwegian older adults: the Tromsø Study 1994-2016.

机构信息

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

出版信息

Eur J Nutr. 2024 Dec;63(8):2987-2998. doi: 10.1007/s00394-024-03482-z. Epub 2024 Aug 28.

Abstract

PURPOSE

To investigate the association between five dietary trajectories over 21 years and frailty in Norwegian older adults.

METHODS

This study used data from three surveys of the Tromsø Study. Diet was measured using food frequency questionnaires at baseline (Tromsø4, 1994-95), after 7 years (Tromsø5, 2001) and at the end of follow-up (Tromsø7, 2015-16). Survey-specific diet scores were constructed based on the Nordic Nutrition Recommendations 2023 and group-based trajectory modelling was used to derive dietary trajectories. At follow-up, frailty was assessed with a 41-item frailty index. Linear regression analysis was performed to assess the associations between dietary trajectories and frailty, adjusted for baseline variables.

RESULTS

Among the 715 participants, 55% were women, with an average age of 54 years at baseline and 74 years at follow-up. The dietary trajectories 'moderately healthy' and 'healthy increase' were associated with a lower frailty index score at follow-up (β = -0.02, 95% confidence interval (CI) = -0.04, -0.002, β = -0.03, 95% CI = -0.06, -0.007), compared with the 'unhealthy' trajectory.

CONCLUSION

Our findings suggest that maintaining a moderately healthy to very healthy diet from mid-life into older age is associated with a lower risk of frailty and supports the promotion of a healthy diet from adulthood to facilitate healthy ageing.

摘要

目的

研究 21 年内 5 种饮食轨迹与挪威老年人虚弱的关系。

方法

本研究使用了特罗姆瑟研究三次调查的数据。在基线(1994-95 年的特罗姆瑟 4 期)、7 年后(2001 年的特罗姆瑟 5 期)和随访结束时(2015-16 年的特罗姆瑟 7 期)使用食物频率问卷测量饮食。根据 2023 年北欧营养建议构建了特定于调查的饮食评分,并使用基于群组的轨迹建模来推导饮食轨迹。在随访时,使用 41 项虚弱指数评估虚弱情况。进行线性回归分析,以评估饮食轨迹与虚弱之间的关联,调整基线变量。

结果

在 715 名参与者中,55%为女性,基线时的平均年龄为 54 岁,随访时的平均年龄为 74 岁。与“不健康”轨迹相比,“较为健康”和“健康增加”的饮食轨迹与随访时较低的虚弱指数得分相关(β=-0.02,95%置信区间(CI)=-0.04,-0.002,β=-0.03,95%CI=-0.06,-0.007)。

结论

我们的研究结果表明,从中年到老年保持较为健康到非常健康的饮食与较低的虚弱风险相关,支持从成年期开始促进健康饮食,以促进健康老龄化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e95/11519092/09499c70b8ed/394_2024_3482_Fig1_HTML.jpg

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