Department of Spine Surgery, Schulthess Klinik, Zurich, Switzerland.
Department of Orthopaedic Surgery and Traumatology, Inselspital, University of Bern, Bern, Switzerland.
Eur Spine J. 2024 Oct;33(10):3737-3748. doi: 10.1007/s00586-024-08425-0. Epub 2024 Aug 28.
Low-grade isthmic and degenerative spondylolisthesis (DS) of the lumbar spine are distinct pathologies but both can be treated with lumbar decompression with fusion. In a very large cohort, we compared patient-reported outcome in relation to the pathology and chief complaint at baseline.
This was a retrospective analysis using the EUROSPINE Spine Tango Registry. We included 582 patients (age 60 ± 15 years; 65% female), divided into four groups based on two variables: type of spondylolisthesis and chief pain complaint (leg pain (LP) versus back pain). Patients completed the COMI preoperatively and up to 5 years follow-up (FU), and rated global treatment outcome (GTO). Regression models were used to predict COMI-scores at FU. Pain scores and satisfaction ratings were analysed.
All patients experienced pronounced reductions in COMI scores. Relative to the other groups, the DS-LP group showed between 5% and 11% greater COMI score reduction (p < 0.01 up to 2 years' FU). This group also performed best with respect to pain outcomes and satisfaction. Long-term GTO was 93% at the 5 year FU, compared with between 82% and 86% in the other groups.
Regardless of the type of spondylolisthesis, all groups experienced an improvement in COMI score after surgery. Patients with DS and LP as their chief complaint appear to benefit more than other patients. These results are the first to show that the type of the spondylolisthesis and its chief complaint have an impact on surgical outcome. They will be informative for the consent process prior to surgery and can be used to build predictive models for individual outcome.
腰椎低度峡部裂性和退变性脊椎滑脱(DS)是两种不同的疾病,但都可以通过减压融合来治疗。在一项大规模队列研究中,我们比较了基线时的病理和主要症状与患者报告的结果之间的关系。
这是一项使用 EUROSPINE Spine Tango 注册中心的回顾性分析。我们纳入了 582 名患者(年龄 60±15 岁;65%为女性),根据两种变量分为四组:脊椎滑脱的类型和主要疼痛主诉(腿痛(LP)与背痛)。患者在术前和随访 5 年(FU)时完成 COMI 评分,并对整体治疗效果(GTO)进行评分。回归模型用于预测 FU 时的 COMI 评分。分析疼痛评分和满意度评分。
所有患者的 COMI 评分均明显降低。与其他组相比,DS-LP 组的 COMI 评分降低幅度更大,在 2 年 FU 时高出 5%至 11%(p<0.01)。该组在疼痛结果和满意度方面也表现最佳。5 年 FU 时的长期 GTO 为 93%,而其他组分别为 82%和 86%。
无论脊椎滑脱的类型如何,所有组在手术后 COMI 评分都有所改善。以 LP 为主要症状的 DS 患者似乎比其他患者受益更多。这些结果首次表明,脊椎滑脱的类型及其主要症状对手术结果有影响。这些结果将为手术前的知情同意过程提供信息,并可用于建立针对个体结果的预测模型。