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48例针对梗阻性心肌病的比奇洛肌切开术的手术结果

[Surgical result of 48 Bigelow myotomies for obstructive myocardiopathy].

作者信息

Mesnildrey P, Gandjbakhch I, Pavie A, Jault F, Mattei M F, Cabrol C

出版信息

Arch Mal Coeur Vaiss. 1985 Jan;78(1):47-53.

PMID:3919679
Abstract

Bigelow's myotomy is one of the surgical options available for the treatment of hypertrophic obstructive cardiomyopathy (HOCM). The results of this operation were analysed in 48 cases operated between 1965 and May 1983. The average age of the patients was relatively low (38 years) but preoperative symptoms were severe (34 patients in Class III and 6 patients in Class IV of the NYHA Classification). The diagnosis was confirmed in all cases by echocardiography, carotid pulse tracings and cardiac catheterisation. 28 patients had associated lesions including 21 cases of mitral regurgitation (minimal in II cases, moderate in 6 cases and severe in 4 cases). All patients underwent Bigelow myotomy which was associated with a complementary procedure in 9 cases (including 2 mitral valve replacements and 2 semi-circular annuloplasties). The hospital mortality was 6 patients; surgical morbidity resulted from permanent intraventricular conduction defects (27 cases). At long-term, 3 more patients died, 2 from cardiac causes. Of the remaining 39 patients followed-up for an average of 32 months, functional improvement was marked, except in very advanced stages of the disease (Class IV) or forms with severe or uncorrected mitral regurgitation. The indications for Bigelow myotomy are discussed with reference to three parameters of HOCM (intraventricular pressure gradient, mitral regurgitation, decreased left ventricular compliance). This procedure has a beneficial effect on the subaortic stenosis and left ventricular compliance. It should be completed by mitral valve surgery in patients with significant regurgitation.

摘要

比奇洛肌切开术是可用于治疗肥厚性梗阻性心肌病(HOCM)的手术选择之一。对1965年至1983年5月期间接受该手术的48例患者的手术结果进行了分析。患者的平均年龄相对较低(38岁),但术前症状严重(纽约心脏协会分级中III级34例,IV级6例)。所有病例均通过超声心动图、颈动脉脉搏描记图和心导管检查确诊。28例患者有相关病变,包括21例二尖瓣反流(轻度2例,中度6例,重度4例)。所有患者均接受了比奇洛肌切开术,其中9例患者还进行了补充手术(包括2例二尖瓣置换术和2例半圆形瓣环成形术)。医院死亡率为6例;手术并发症为永久性室内传导缺陷(27例)。长期来看,又有3例患者死亡,2例死于心脏原因。在其余平均随访32个月的39例患者中,除疾病非常晚期(IV级)或存在严重或未纠正的二尖瓣反流的类型外,功能改善明显。参考HOCM的三个参数(室内压力梯度、二尖瓣反流、左心室顺应性降低)讨论了比奇洛肌切开术的适应证。该手术对主动脉瓣下狭窄和左心室顺应性有有益影响。对于有明显反流的患者,应通过二尖瓣手术来完善治疗。

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