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体外膜肺氧合联合血液灌流辅助抢救乌头碱中毒:1例报告

Extracorporeal membrane oxygenation combined with hemoperfusion to assist in the rescue of aconitine poisoning: A case report.

作者信息

Zhao Zhiwen, Fang Zhicheng

机构信息

Department of Emergency Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, China.

出版信息

Perfusion. 2025 May;40(4):1062-1067. doi: 10.1177/02676591241280163. Epub 2024 Aug 28.

Abstract

Extracorporeal membrane oxygenation (ECMO) has been widely used as a clinical bridge for cardiopulmonary failure. We recently used combined veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and haemoperfusion to successfully treat a patient with acute aconitine poisoning. The patient was admitted to the Emergency Intensive Care Unit (EICU) in a state of coma and shock. Her received comprehensive treatment, including haemoperfusion and anti-shock therapy. 40 minutes after admission, the patient experienced sudden respiratory and cardiac arrest. After conventional defibrillation and cardiopulmonary resuscitation proved ineffective, veno-arterial ECMO was immediately initiated. One hour after initiation of VA-ECMO, the patient's heart rhythm stabilised to sinus rhythm. After 33 h of supportive care, the patient was awake, haemodynamically stable and the VA-ECMO was successfully removed. The patient made full recovery 7 days after admission.

摘要

体外膜肺氧合(ECMO)已被广泛用作心肺功能衰竭的临床桥梁。我们最近使用静脉-动脉体外膜肺氧合(VA-ECMO)联合血液灌流成功治疗了一名急性乌头碱中毒患者。该患者以昏迷和休克状态被收入急诊重症监护病房(EICU)。她接受了包括血液灌流和抗休克治疗在内的综合治疗。入院40分钟后,患者突然出现呼吸和心脏骤停。在常规除颤和心肺复苏无效后,立即启动了静脉-动脉ECMO。启动VA-ECMO 1小时后,患者的心律稳定为窦性心律。经过33小时的支持治疗,患者清醒,血流动力学稳定,VA-ECMO成功撤除。患者入院7天后完全康复。

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