Department of Clinical Nursing, Kochi Medical School, Kochi, Japan;
Center for Photodynamic Medicine, Kochi Medical School, Kochi, Japan.
Anticancer Res. 2024 Sep;44(9):3937-3943. doi: 10.21873/anticanres.17222.
BACKGROUND/AIM: Intraoperative identification of the cancer location is often difficult during robot-assisted surgery, especially in early stage cancers. This study aimed to investigate the feasibility and accuracy of a novel endoscopic clip emitting near-infrared (NIR) fluorescence during robot-assisted surgery for gastrointestinal cancer.
Preoperative placement of endoscopic marking clips equipped with NIR fluorescent resin was performed to determine the resection margins in six patients with gastrointestinal cancer. During robot-assisted surgery, a NIR fluorescence imaging system was used to detect the fluorescence. The evaluation examined whether fluorescence from the clips was visualized during robot-assisted surgery.
The NIR fluorescent signals emitted from the clips were successfully detected in all six patients from the serosal surfaces, resulting in the quick and accurate identification of the resection line. There were no significant differences in age, sex, or body mass index between the patients in whom we could detect NIR fluorescence.
This novel NIR fluorescent clip is a promising diagnostic tool for accurately detecting tumor locations during robot-assisted surgery for gastrointestinal cancer.
背景/目的：在机器人辅助手术中，尤其是在早期癌症中，术中确定癌症位置通常较为困难。本研究旨在探讨新型内镜夹在机器人辅助胃肠道癌症手术中发射近红外（NIR）荧光的可行性和准确性。
对 6 例胃肠道癌症患者进行术前内镜标记夹放置，夹内带有近红外荧光树脂，以确定切除边界。在机器人辅助手术期间，使用近红外荧光成像系统检测荧光。评估内容包括检测在机器人辅助手术期间能否观察到荧光。
在所有 6 例患者中，均成功从浆膜表面检测到夹发出的 NIR 荧光信号，从而快速、准确地识别了切除线。在能够检测到 NIR 荧光的患者中，其年龄、性别或体重指数无显著差异。
新型近红外荧光夹是一种很有前途的诊断工具，可用于在机器人辅助胃肠道癌症手术中准确检测肿瘤位置。
