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拉美国家的献血者问卷和传染病筛查。

Blood donor questionnaires and infectious disease screening in Latin American countries.

机构信息

Department of Laboratory Medicine, UCSF, San Francisco, California, USA.

School of Medicine and Health Science, Public Health Research Group, Universidad del Rosario, Bogotá, Colombia.

出版信息

Vox Sang. 2024 Nov;119(11):1201-1206. doi: 10.1111/vox.13730. Epub 2024 Aug 28.

DOI:10.1111/vox.13730
PMID:39198032
Abstract

BACKGROUND AND OBJECTIVES

Blood donor questionnaires are tools used to screen prospective blood donors to determine their eligibility. There are limited data regarding blood donor questionnaires and infectious disease screening of the blood supply in Latin American countries. This study aimed to survey donor centres in Latin American countries to learn more about blood donor screening and infection assessment.

MATERIALS AND METHODS

An international team of transfusion medicine professionals including medical directors and supervisors who work or collaborate with Latin American donor centres, called 'Comité de Investigación en Medicina Transfusional', designed a survey (16 questions) to characterize blood donor eligibility in Latin America.

RESULTS

Eighty-two institutions from 14 Latin American countries responded to the survey. Most donor centres (66%; 54 of 82) had a donor deferral percentage between 5% and 25%, and the most common causes of deferrals were low haemoglobin and high-risk behaviour. Most donors in blood centres were directed family donors compared with voluntary donors. Infection evaluation included mostly serologic assessment (81%; 30 of 37) for human immunodeficiency virus (HIV), Hepatitis B, Hepatitis C, Treponema pallidum and Trypanosoma cruzi rather than nucleic acid tests (5%; 2 of 37).

CONCLUSION

Heterogeneity exists in donor selection and infectious disease screening in Latin American countries. This survey provides valuable information to understand Latin American blood centre practices.

摘要

背景与目的

献血者问卷是用于筛选潜在献血者以确定其资格的工具。关于拉丁美洲国家的献血者问卷和血液供应传染病筛查的数据有限。本研究旨在调查拉丁美洲国家的献血中心,以更多地了解血液筛查和感染评估。

材料与方法

一个由输血医学专业人员组成的国际团队,包括与拉丁美洲献血中心合作或合作的医学主任和主管,称为“Comité de Investigación en Medicina Transfusional”,设计了一项调查(16 个问题),以描述拉丁美洲的献血者资格。

结果

来自 14 个拉丁美洲国家的 82 个机构对该调查做出了回应。大多数献血中心(66%;82 个中的 54 个)的献血者延迟百分比在 5%至 25%之间,最常见的延迟原因是低血红蛋白和高风险行为。与志愿献血者相比,血液中心的大多数献血者是定向家庭献血者。感染评估主要包括针对人类免疫缺陷病毒(HIV)、乙型肝炎、丙型肝炎、梅毒螺旋体和克氏锥虫的血清学评估(81%;37 个中的 30 个),而不是核酸检测(5%;37 个中的 2 个)。

结论

拉丁美洲国家在献血者选择和传染病筛查方面存在异质性。这项调查提供了有价值的信息,有助于了解拉丁美洲血液中心的实践。

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