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中国环境细颗粒物所致卒中负担的变化。

Changes on Stroke Burden Attributable to Ambient Fine Particulate Matter in China.

机构信息

Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China;Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences, Beijing 100037, China.

Department of Clinical Epidemiology and Biostatistics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Disease, Chongqing 400016, China.

出版信息

Biomed Environ Sci. 2024 Aug 20;37(8):823-833. doi: 10.3967/bes2024.083.

DOI:10.3967/bes2024.083

PMID:39198248

Abstract

OBJECTIVE

In recent decades, China has implemented a series of policies to address air pollution. We aimed to assess the health effects of these policies on stroke burden attributable to ambient fine particulate matter (PM ).

METHODS

regression was applied to explore the temporal tendency of stroke burden based on data from the Global Burden of Disease 2019 study.

RESULTS

The age-standardized rates of disability-adjusted life year (DALY) for stroke attributable to ambient PM in China, increased dramatically during 1990-2012, subsequently decreased at an annual percentage change (APC) of -1.98 [95% confidence interval ( ): -2.26, -1.71] during 2012-2019. For ischemic stroke (IS), the age-standardized DALY rates doubled from 1990 to 2014, and decreased at an APC of -0.83 (95% : -1.33, -0.33) during 2014-2019. Intracerebral hemorrhage (ICH) showed a substantial increase in age-standardized DALY rates from 1990 to 2003, followed by declining trends, with APCs of -1.46 (95% : -2.74, -0.16) during 2003-2007 and -3.33 (95% : -3.61, -3.06) during 2011-2019, respectively. Conversely, the age-standardized DALY rates for subarachnoid hemorrhage (SAH) generally declined during 1990-2019.

CONCLUSION

Our results clarified the dynamic changes of the ambient PM attributable stroke burden in China during 1990-2019, highlighting the health effects of air quality improvement policies.

摘要

目的

近几十年来，中国实施了一系列政策来应对空气污染。我们旨在评估这些政策对归因于环境细颗粒物（PM ）的卒中负担的健康影响。

方法

应用回归分析方法，基于 2019 年全球疾病负担研究的数据，探讨卒中负担的时间趋势。

结果

中国归因于环境 PM 的卒中残疾调整生命年（DALY）年龄标化率在 1990-2012 年期间显著增加，随后在 2012-2019 年期间以每年-1.98%的百分比变化（APC）下降（95%置信区间[CI]：-2.26，-1.71）。对于缺血性卒中（IS），1990 年至 2014 年期间年龄标化 DALY 率增加了一倍，在 2014-2019 年期间以每年-0.83%的 APC 下降（95%CI：-1.33，-0.33）。脑出血（ICH）的年龄标化 DALY 率从 1990 年到 2003 年显著增加，随后呈下降趋势，2003-2007 年期间 APC 为-1.46（95%CI：-2.74，-0.16），2011-2019 年期间 APC 为-3.33（95%CI：-3.61，-3.06）。相反，蛛网膜下腔出血（SAH）的年龄标化 DALY 率在 1990-2019 年期间普遍下降。