Konno Takuya, Shimizu Tomohiro, Inoue Masahiro, Masuda Takeshi, Terkawi Mohamad Alaa, Iwasaki Norimasa, Takahashi Daisuke
Department of Orthopaedic Surgery, Wajokai Eniwa Hospital, Eniwa 061-1449, Japan.
Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan.
Bioengineering (Basel). 2024 Aug 19;11(8):841. doi: 10.3390/bioengineering11080841.
In patients with severe hip dysplasia, total hip arthroplasty (THA) using bulk bone graft (BBG) enhances anatomic cup positioning and provides early structural support. This study assesses the mid-term outcomes of THA with BBG in patients with over 50% graft bone coverage. Among 1951 patients who underwent THA between 2003 and 2007, 183 had BBG. After excluding early dropouts and infections, 151 patients remained. They were classified into uncovered (<50% coverage, 79 patients) and covered (>50% coverage, 72 patients) groups. The efficacy of cup fixation was compared between these groups. After ten years, the survival rate for not needing THA revision was 98% in the uncovered group and 100% in the covered group, while the rate for radiographic stability was 93% versus 99%, respectively. Although the cutoff value for the uncovered portion could not be clarified in this study, the mid-term results for 50% to approximately 70% uncovered were comparable to those for 50% or lesser, which have previously been expected to perform well. Recently, biomechanically advantageous bone grafting techniques have been identified, and based on the results of this study, it may be possible to expand the indications for THA with bone grafting for developmental dysplasia of the hip.
在严重髋关节发育不良患者中,使用大块骨移植(BBG)进行全髋关节置换术(THA)可改善髋臼假体的解剖位置并提供早期结构支撑。本研究评估了骨移植覆盖率超过50%的患者行THA联合BBG的中期疗效。在2003年至2007年间接受THA的1951例患者中,183例采用了BBG。排除早期退出者和感染者后,剩余151例患者。他们被分为未覆盖组(覆盖率<50%,79例)和覆盖组(覆盖率>50%,72例)。比较了两组间髋臼假体固定的疗效。十年后,未覆盖组不需要THA翻修的生存率为98%,覆盖组为100%,而影像学稳定率分别为93%和99%。尽管本研究未能明确未覆盖部分的临界值,但未覆盖50%至约70%的中期结果与未覆盖50%或更低的结果相当,而后者此前被认为效果良好。最近,已确定了具有生物力学优势的骨移植技术,基于本研究结果,可能扩大髋关节发育不良行骨移植THA的适应症。