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三尖瓣反流治疗的新进展

New Therapeutic Advances in the Management of Tricuspid Valve Regurgitation.

作者信息

Synetos Andreas, Ktenopoulos Nikolaos, Katsaros Odysseas, Vlasopoulou Konstantina, Korovesis Theofanis, Drakopoulou Maria, Apostolos Anastasios, Koliastasis Leonidas, Toutouzas Konstantinos, Tsioufis Constantinos

机构信息

First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, 11527 Athens, Greece.

School of Medicine, European University of Cyprus, Egkomi 2404, Cyprus.

出版信息

J Clin Med. 2024 Aug 6;13(16):4599. doi: 10.3390/jcm13164599.

Abstract

Tricuspid regurgitation (TR) is an intricate disorder that has a negative outlook, while surgical treatment is linked to increased mortality. Primary TR occurs due to a structural defect in the tricuspid valve (TV), while secondary TR is a more prevalent condition often associated with pulmonary hypertension, heart failure, and atrial fibrillation. The use of specific surgical procedures to improve TR is limited in everyday clinical practice due to the heightened surgical risk and delayed patient presentation. The development of other transcatheter heart valve procedures has led to a significant increase in transcatheter TV operations, which can be attributed to certain technological advancements. This review aims to provide an updated overview of transcatheter TV procedures, available alternative therapies, and standards for patient selection. It will also highlight the current state of development in this field, which is characterized by rapid progress and numerous ongoing clinical trials.

摘要

三尖瓣反流(TR)是一种复杂的疾病,预后不良,而手术治疗与死亡率增加相关。原发性TR是由于三尖瓣(TV)结构缺陷引起的,而继发性TR是一种更常见的情况,通常与肺动脉高压、心力衰竭和心房颤动有关。由于手术风险增加和患者就诊延迟,在日常临床实践中,使用特定手术方法改善TR的情况有限。其他经导管心脏瓣膜手术的发展导致经导管TV手术显著增加,这可归因于某些技术进步。本综述旨在提供经导管TV手术、可用替代疗法及患者选择标准的最新概述。它还将强调该领域的当前发展状况,其特点是进展迅速且有众多正在进行的临床试验。

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