猪下丘脑 - 垂体功能的个体发生。I. 胎儿和新生儿垂体中的促黄体生成素（LH）和促卵泡生成素（FSH）。

The ontogeny of hypothalamic pituitary function in the pig. I. Pituitary LH and FSH in the fetus and neonate.

作者信息

McNamara M, Vandalem J L, Hennen G, Colenbrander B, MacDonald A A, Van de Wiel D, Meijer J

出版信息

Mol Cell Endocrinol. 1985 Feb;39(2):119-24. doi: 10.1016/0303-7207(85)90128-5.

PMID:3920094

Abstract

Pituitaries were collected from fetal and postnatal pigs from day 55 p.c. until 6 weeks after birth at closely spaced intervals. LH and FSH in individual pituitaries were quantified by both homologous RIA and homologous RRA. No significant difference was found between results obtained by RIA and RRA. Both LH and FSH are first detected by RIA and RRA in the porcine fetal pituitary at 75 days p.c. Thereafter both LH and FSH pituitary content rises until term. LH pituitary concentration in both male and female fetuses and FSH pituitary concentration in males exhibit a peak just before birth. FSH pituitary concentration in females rises until birth and thereafter remains elevated. A statistically significant sex difference was found postnatally with regard to FSH content and concentration but not for LH.

摘要

从妊娠55天的胎儿猪到出生后6周的仔猪，以紧密间隔的时间点采集垂体。通过同源放射免疫分析（RIA）和同源放射受体分析（RRA）对单个垂体中的促黄体生成素（LH）和促卵泡生成素（FSH）进行定量。RIA和RRA获得的结果之间未发现显著差异。在妊娠75天时，通过RIA和RRA首次在猪胎儿垂体中检测到LH和FSH。此后，LH和FSH的垂体含量均持续上升直至足月。雄性和雌性胎儿的LH垂体浓度以及雄性的FSH垂体浓度在出生前出现峰值。雌性的FSH垂体浓度在出生前持续上升，出生后仍保持升高。出生后，在FSH含量和浓度方面发现了具有统计学意义的性别差异，但LH未发现此差异。