Dimri Inon, Roguin Ariel, Hamuda Nashed, Abu Fanne Rami, Barel Maguli, Leshem Eran, Kobo Ofer, Margolis Gilad
Department of Cardiology, Hillel Yaffe Medical Centre, Hadera 3820302, Israel.
The Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa 3525433, Israel.
J Clin Med. 2024 Aug 15;13(16):4813. doi: 10.3390/jcm13164813.
: During the first months of the COVID-19 outbreak, an increase was observed in atrial fibrillation (AF)-related mortality in the United States (U.S). We aimed to investigate AF-related mortality trends in the U.S. before, during, and after the COVID-19 pandemic peak, stratified by sociodemographic factors. : using the Wide-Ranging Online Data for Epidemiologic Research database of the Centers for Disease Control and Prevention, we compared the AF-related age-adjusted mortality rate (AAMR) among different subgroups in the two years preceding, during, and following the pandemic peak (2018-2019, 2020-2021, 2022-2023). : By analyzing a total of 1,267,758 AF-related death cases, a significant increase of 24.8% was observed in AF-related mortality during the pandemic outbreak, followed by a modest significant decrease of 1.4% during the decline phase of the pandemic. The most prominent increase in AF-related mortality was observed among males, among individuals younger than 65 years, and among individuals of African American and Hispanic descent, while males, African American individuals, and multiracial individuals experienced a non-statistically significant decrease in AF-related mortality during the pandemic decline period. : Our findings suggest that in future healthcare crises, targeted healthcare policies and interventions to identify AF, given its impact on patients' outcomes, should be developed while addressing disparities among different patient populations.
在新冠疫情爆发的最初几个月，美国房颤（AF）相关死亡率有所上升。我们旨在调查新冠疫情高峰期之前、期间和之后美国房颤相关死亡率趋势，并按社会人口学因素进行分层。利用美国疾病控制与预防中心的广泛在线流行病学研究数据库，我们比较了疫情高峰期之前、期间和之后两年（2018 - 2019年、2020 - 2021年、2022 - 2023年）不同亚组中与房颤相关的年龄调整死亡率（AAMR）。通过分析总共1267758例房颤相关死亡病例，我们观察到疫情爆发期间房颤相关死亡率显著上升24.8%，随后在疫情下降阶段适度显著下降1.4%。房颤相关死亡率最显著的上升出现在男性、65岁以下个体以及非裔美国人和西班牙裔个体中，而男性、非裔美国人个体和多种族个体在疫情下降期间房颤相关死亡率出现了非统计学显著下降。我们的研究结果表明，在未来的医疗危机中，鉴于房颤对患者预后的影响，应制定有针对性的医疗政策和干预措施来识别房颤，同时解决不同患者群体之间的差异。
