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应激性心肌病:围产期与普通人群的差异

Takotsubo Syndrome: Differences between Peripartum Period and General Population.

作者信息

Tzerefos Stavros, Aloizou Dimitra, Nikolakopoulou Sofia, Aloizos Stavros

机构信息

ICU Department, IASO General and Maternity Hospital, 151 23 Athens, Greece.

Emergency Department, Asklepieion General Hospital, 166 73 Voula, Greece.

出版信息

Healthcare (Basel). 2024 Aug 12;12(16):1602. doi: 10.3390/healthcare12161602.

Abstract

Takotsubo syndrome (TTS) was first described in postmenopausal women with transient regional wall motion abnormalities. The trigger is usually an emotional or physical stress. The catecholamine hypothesis seems to be the most prevailing. The main difference between TTS and acute coronary syndromes is that there is no obstructive coronary disease to explain the regional abnormalities. In this form, the left ventricle resembles the fishing jar which is used to trap octopus in Japan. However, to date more atypical forms are recognized. Also, the syndrome is not limited to older women. Nowadays, TTS is presented even in pregnancy and postpartum females. Our experience revealed cases of patients during these periods and some of them suffered from reverse Takotsubo. Additionally, the initial diagnosis in some patients was other than TTS. Due to these findings, we suggest that this type of TTS is not very rare but underestimated. For this reason, further studies are needed to support and explain this condition.

摘要

应激性心肌病(TTS)最初是在绝经后女性中被描述的,伴有短暂的局部室壁运动异常。诱发因素通常是情绪或身体上的应激。儿茶酚胺假说似乎最为流行。TTS与急性冠脉综合征的主要区别在于,不存在阻塞性冠状动脉疾病来解释局部异常。在这种情况下,左心室类似于日本用来捕捉章鱼的渔瓮。然而,迄今为止,更多非典型形式被认识到。此外,该综合征并不局限于老年女性。如今,TTS甚至在孕期和产后女性中也有出现。我们的经验揭示了这些时期患者的病例,其中一些患有反向应激性心肌病。此外,一些患者的初始诊断并非TTS。基于这些发现,我们认为这种类型的TTS并非非常罕见,而是被低估了。因此,需要进一步的研究来支持和解释这种情况。

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