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应激性心肌病:围产期与普通人群的差异

Takotsubo Syndrome: Differences between Peripartum Period and General Population.

作者信息

Tzerefos Stavros, Aloizou Dimitra, Nikolakopoulou Sofia, Aloizos Stavros

机构信息

ICU Department, IASO General and Maternity Hospital, 151 23 Athens, Greece.

Emergency Department, Asklepieion General Hospital, 166 73 Voula, Greece.

出版信息

Healthcare (Basel). 2024 Aug 12;12(16):1602. doi: 10.3390/healthcare12161602.

DOI:10.3390/healthcare12161602
PMID:39201162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11354156/
Abstract

Takotsubo syndrome (TTS) was first described in postmenopausal women with transient regional wall motion abnormalities. The trigger is usually an emotional or physical stress. The catecholamine hypothesis seems to be the most prevailing. The main difference between TTS and acute coronary syndromes is that there is no obstructive coronary disease to explain the regional abnormalities. In this form, the left ventricle resembles the fishing jar which is used to trap octopus in Japan. However, to date more atypical forms are recognized. Also, the syndrome is not limited to older women. Nowadays, TTS is presented even in pregnancy and postpartum females. Our experience revealed cases of patients during these periods and some of them suffered from reverse Takotsubo. Additionally, the initial diagnosis in some patients was other than TTS. Due to these findings, we suggest that this type of TTS is not very rare but underestimated. For this reason, further studies are needed to support and explain this condition.

摘要

应激性心肌病(TTS)最初是在绝经后女性中被描述的,伴有短暂的局部室壁运动异常。诱发因素通常是情绪或身体上的应激。儿茶酚胺假说似乎最为流行。TTS与急性冠脉综合征的主要区别在于,不存在阻塞性冠状动脉疾病来解释局部异常。在这种情况下,左心室类似于日本用来捕捉章鱼的渔瓮。然而,迄今为止,更多非典型形式被认识到。此外,该综合征并不局限于老年女性。如今,TTS甚至在孕期和产后女性中也有出现。我们的经验揭示了这些时期患者的病例,其中一些患有反向应激性心肌病。此外,一些患者的初始诊断并非TTS。基于这些发现,我们认为这种类型的TTS并非非常罕见,而是被低估了。因此,需要进一步的研究来支持和解释这种情况。

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Takotsubo Syndrome: Differences between Peripartum Period and General Population.应激性心肌病:围产期与普通人群的差异
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本文引用的文献

1
Pregnancy-associated takotsubo cardiomyopathy hospitalizations in the United States.美国妊娠相关性应激性心肌病住院治疗情况。
Am J Physiol Heart Circ Physiol. 2023 Sep 1;325(3):H468-H474. doi: 10.1152/ajpheart.00262.2023. Epub 2023 Jul 7.
2
Cardioprotective Role of Estrogen in Takotsubo Cardiomyopathy.雌激素在应激性心肌病中的心脏保护作用
Cureus. 2022 Mar 4;14(3):e22845. doi: 10.7759/cureus.22845. eCollection 2022 Mar.
3
Intraventricular Thrombus Formation and Embolism in Takotsubo Syndrome: Insights From the International Takotsubo Registry.
Takotsubo 综合征患者的室腔内血栓形成与栓塞:国际 Takotsubo 注册研究的新认识。
Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):279-287. doi: 10.1161/ATVBAHA.119.313491. Epub 2019 Nov 26.
4
Reverse Takotsubo cardiomyopathy: a comprehensive review.反向性应激性心肌病:全面综述
Ann Transl Med. 2018 Dec;6(23):460. doi: 10.21037/atm.2018.11.08.
5
International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology.国际 Takotsubo 综合征专家共识文件(第一部分):临床特征、诊断标准和病理生理学。
Eur Heart J. 2018 Jun 7;39(22):2032-2046. doi: 10.1093/eurheartj/ehy076.
6
International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management.国际 Takotsubo 综合征专家共识文件(第二部分):诊断检查、预后和管理。
Eur Heart J. 2018 Jun 7;39(22):2047-2062. doi: 10.1093/eurheartj/ehy077.
7
Takotsubo Syndrome After Cesarean Section: Rare But Possible.剖宫产术后应激性心肌病:罕见但有可能发生。
J Am Coll Cardiol. 2018 Apr 24;71(16):1838-1839. doi: 10.1016/j.jacc.2018.02.035.
8
Pathophysiology of Takotsubo Syndrome.Takotsubo 综合征的病理生理学。
Circulation. 2017 Jun 13;135(24):2426-2441. doi: 10.1161/CIRCULATIONAHA.116.027121.
9
Optical Coherence Tomography to Evaluate Plaque Burden and Morphology in Patients With Takotsubo Syndrome.光学相干断层扫描评估应激性心肌病患者的斑块负荷和形态
J Am Heart Assoc. 2016 Dec 22;5(12):e004474. doi: 10.1161/JAHA.116.004474.
10
A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry.一种新型的临床评分(InterTAK 诊断评分)用于鉴别心尖球形综合征与急性冠状动脉综合征:国际心尖球形综合征注册研究结果。
Eur J Heart Fail. 2017 Aug;19(8):1036-1042. doi: 10.1002/ejhf.683. Epub 2016 Dec 7.