Watters D A, Smith A N, Eastwood M A, Anderson K C, Elton R A, Mugerwa J W
Gut. 1985 Apr;26(4):384-92. doi: 10.1136/gut.26.4.384.
The tensile properties of the colon have been examined using methods which gave repeatable results. They showed little change after storage in salt for up to five weeks. The burst strength remained unchanged along the length of the colon. The tensile strength fell distally, as the thickness of the colonic wall increased. The width at burst decreased distally as did the internal diameter. The visco-elastic property of stress relaxation was constant in all regions. The tensile property of the colon was well developed at birth, but fell with age as did the width at burst and the internal diameter. Stress relaxation was unaffected. Because there may be a mechanical abnormality of the colonic wall in diverticular disease and as Europeans are prone to this condition while Africans are not commonly affected, European and African colons were compared. The tensile strength in a Kampala group was greater than in an Edinburgh one, but fell significantly in both groups with age. The width at burst was greater in the Kampala group, but also declined with age. Stress-relaxation was similar in both groups. In view of the similar properties in childhood of colons from Edinburgh and Kampala, the strength of the adult African compared with European colons may derive later from environmental factors such as diet. There were, however, no differences between the colons with and without diverticular disease in European subjects over the age of 50 years.
已使用能得出可重复结果的方法对结肠的拉伸特性进行了检测。将结肠置于盐溶液中储存长达五周后，其拉伸特性几乎没有变化。结肠各部位的破裂强度保持不变。随着结肠壁厚度增加，拉伸强度向远端下降。破裂时的宽度以及内径均向远端减小。应力松弛的粘弹性特性在所有区域都是恒定的。结肠的拉伸特性在出生时就已发育良好，但会随着年龄增长而下降，破裂时的宽度和内径也是如此。应力松弛不受影响。由于憩室病患者的结肠壁可能存在机械异常，且欧洲人易患此病，而非洲人通常不受影响，因此对欧洲人和非洲人的结肠进行了比较。坎帕拉组的拉伸强度高于爱丁堡组，但两组的拉伸强度均随年龄显著下降。坎帕拉组破裂时的宽度更大，但也随年龄减小。两组的应力松弛情况相似。鉴于爱丁堡和坎帕拉儿童结肠的特性相似，成年非洲人与欧洲人结肠强度的差异可能稍后源于饮食等环境因素。然而，在50岁以上的欧洲受试者中，有憩室病和无憩室病的结肠之间没有差异。
