Watters D A, Smith A N, Eastwood M A, Anderson K C, Elton R A
Q J Exp Physiol. 1985 Jan;70(1):151-62. doi: 10.1113/expphysiol.1985.sp002887.
The mechanical properties of the rat colon were studied in old and young Sprague-Dawley rats which were also grouped by sex. Different storage media were used. Rings of colonic tissue were submitted to pulls on an Instron 1026 tensiometer. Gender did not affect the properties of the young rat colon. The rat colon has a tensile strength of around 50 g/mm2 (which places it between the dog and the cat). It increased in strength from proximal to distal, though the rectum was weaker than the colon. The pre-strain of the rat colon was 10% and it was capable of stretching to 200% of its original dimensions. The strength and ability to stretch fell with age, although it initially increased, in the first year of life. Physiological saline at 4 degrees C preserved the burst strength, percentage elongation, hysteresis and Young's modulus between 25 and 100 g stress for up to 1 week. Young's modulus between 125 and 200 g fell progressively with each day of storage. Stress relaxation rose in the first 24 h and thereafter remained constant. Salt appeared to be a good long-term storage medium. Irradiation of the colons before storage did not affect the mechanical properties.
在老年和幼年的斯普拉格-道利大鼠中研究了大鼠结肠的力学性能，这些大鼠也按性别分组。使用了不同的储存介质。将结肠组织环置于英斯特朗1026拉力试验机上进行拉伸。性别不影响幼年大鼠结肠的性能。大鼠结肠的抗张强度约为50克/平方毫米（介于狗和猫之间）。其强度从近端到远端逐渐增加，不过直肠比结肠弱。大鼠结肠的预应变是10%，它能够拉伸至其原始尺寸的200%。强度和拉伸能力随年龄下降，尽管在生命的第一年它最初有所增加。4℃的生理盐水可在长达1周的时间内保持25至100克应力下的破裂强度、伸长百分比、滞后现象和杨氏模量。125至200克应力下的杨氏模量随储存天数逐渐下降。应力松弛在最初24小时内上升，此后保持恒定。盐似乎是一种良好的长期储存介质。储存前对结肠进行辐照不影响力学性能。
