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药物传递策略治疗与年龄相关的疾病。

Drug Delivery Strategies for Age-Related Diseases.

机构信息

Division of Pharmaceutics, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University, 1-1-1 Daigaku-Dori, Sanyo Onoda 756-0884, Japan.

出版信息

Int J Mol Sci. 2024 Aug 9;25(16):8693. doi: 10.3390/ijms25168693.

Abstract

Drug delivery systems (DDSs) enable the controlled release of drugs in the body. DDSs have attracted increasing attention for the treatment of various disorders, including cancer, inflammatory diseases, and age-related diseases. With recent advancements in our understanding of the molecular mechanisms of aging, new target molecules and drug delivery carriers for age-related diseases have been reported. In this review, we will summarize the recent research on DDSs for age-related diseases and identify DDS strategies in the treatment of age-related diseases.

摘要

药物传递系统(DDS)能够实现药物在体内的控制释放。DDS 因其在治疗各种疾病(包括癌症、炎症性疾病和与年龄相关的疾病)方面的应用而受到越来越多的关注。随着我们对衰老分子机制认识的不断深入,新的与年龄相关的疾病的靶分子和药物传递载体也被报道出来。在这篇综述中,我们将总结最近关于用于治疗与年龄相关的疾病的 DDS 的研究,并确定治疗与年龄相关的疾病的 DDS 策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d196/11354581/8a133c93bde8/ijms-25-08693-g001.jpg

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