Division of Pharmaceutics, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University, 1-1-1 Daigaku-Dori, Sanyo Onoda 756-0884, Japan.
Int J Mol Sci. 2024 Aug 9;25(16):8693. doi: 10.3390/ijms25168693.
Drug delivery systems (DDSs) enable the controlled release of drugs in the body. DDSs have attracted increasing attention for the treatment of various disorders, including cancer, inflammatory diseases, and age-related diseases. With recent advancements in our understanding of the molecular mechanisms of aging, new target molecules and drug delivery carriers for age-related diseases have been reported. In this review, we will summarize the recent research on DDSs for age-related diseases and identify DDS strategies in the treatment of age-related diseases.
药物传递系统(DDS)能够实现药物在体内的控制释放。DDS 因其在治疗各种疾病(包括癌症、炎症性疾病和与年龄相关的疾病)方面的应用而受到越来越多的关注。随着我们对衰老分子机制认识的不断深入,新的与年龄相关的疾病的靶分子和药物传递载体也被报道出来。在这篇综述中,我们将总结最近关于用于治疗与年龄相关的疾病的 DDS 的研究,并确定治疗与年龄相关的疾病的 DDS 策略。