Feder H H, Goy R W
Horm Behav. 1985 Mar;19(1):104-9. doi: 10.1016/0018-506x(85)90011-x.
Prepubertal (21-24 days of age), intact female guinea pigs treated sequentially with estradiol benzoate and LH or FSH displayed lordosis behavior. The gonadotropins apparently caused release of progesterone from the ovaries, because lordosis behavior in guinea pigs is activated by sequential action of estrogen and progesterone. These data demonstrate that immature ovaries, completely devoid of corpus luteum tissue, are capable of secreting behaviorally significant concentrations of progesterone when stimulated by gonadotropins. Therefore, the luteal compartment of the guinea pig ovary is not essential for the preovulatory surges of progesterone that coincide with expression of lordosis behavior in adulthood. Likely candidates for sources of preovulatory progesterone in prepubertal females are antral follicle and interstitial gland tissue.
对青春期前（21 - 24日龄）完整的雌性豚鼠依次用苯甲酸雌二醇和促黄体生成素（LH）或促卵泡生成素（FSH）进行处理，它们会表现出脊柱前凸行为。促性腺激素显然促使卵巢释放孕酮，因为豚鼠的脊柱前凸行为是由雌激素和孕酮的相继作用所激活的。这些数据表明，完全没有黄体组织的未成熟卵巢，在受到促性腺激素刺激时，能够分泌出对行为有显著影响浓度的孕酮。因此，豚鼠卵巢的黄体部分对于成年期与脊柱前凸行为表达同时出现的排卵前孕酮激增并非必不可少。青春期前雌性动物排卵前孕酮的可能来源是窦状卵泡和间质腺组织。
