De Bernardo Maddalena, Cione Ferdinando, De Pascale Ilaria, Pagliarulo Sergio, Rosa Nicola
Eye Unit, Department of Medicine Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Salerno, Italy.
J Pers Med. 2024 Aug 4;14(8):826. doi: 10.3390/jpm14080826.
In this study, intraocular pressure (IOP) was measured in sitting, supine, prone, and standing (ST) positions and again five minutes after standing (ST-5) utilizing a Tono-Pen AVIA in 124 eyes of 62 healthy subjects with ages ranging from 21 to 59 years (mean 30 ± 10 years). In each subject, the average IOP of both eyes was used for the statistical evaluation. The mean IOP difference between the ST and sitting positions was -0.13 ± 1.63 mmHg ( = 0.548); between ST-5 and sitting, it was 0.53 ± 1.24 mmHg ( = 0.001); between supine and sitting, it was 1.30 ± 1.48 mmHg ( < 0.001); between ST and supine, it was -1.43 ± 1.74 mmHg ( < 0.001); between ST-5 and supine, it was -0.77 ± 1.59 mmHg ( < 0.001); between prone and supine, it was 2.24 ± 1.92 mmHg ( < 0.001); between ST and ST-5, it was -0.67 ± 1.84 mmHg (range: -7.5 to 5 mmHg) ( = 0.007); between prone and ST, it was 3.46 ± 2.01 mmHg ( < 0.001); between ST-5 and prone, it was -2.46 ± 1.67 mmHg ( < 0.001); and between sitting and prone, it was -3.22 ± 1.56 mmHg ( < 0.001). The results show a significant IOP increase in the ST-5 position, suggesting that such measurements need to be performed in an attempt to explain the progression of glaucoma in apparently normal-tension patients.
在本研究中，使用托诺笔AVIA眼压计对62名年龄在21至59岁（平均30±10岁）的健康受试者的124只眼睛，在坐位、仰卧位、俯卧位和站立位（ST）测量眼压，并在站立5分钟后（ST - 5）再次测量。在每个受试者中，双眼的平均眼压用于统计评估。站立位与坐位之间的平均眼压差异为-0.13±1.63 mmHg（P = 0.548）；ST - 5与坐位之间为0.53±1.24 mmHg（P = 0.001）；仰卧位与坐位之间为1.30±1.48 mmHg（P < 0.001）；站立位与仰卧位之间为-1.43±1.74 mmHg（P < 0.001）；ST - 5与仰卧位之间为-0.77±1.59 mmHg（P < 0.001）；俯卧位与仰卧位之间为2.24±1.92 mmHg（P < 0.001）；站立位与ST - 5之间为-0.67±1.84 mmHg（范围：-7.5至5 mmHg）（P = 0.007）；俯卧位与站立位之间为3.46±2.01 mmHg（P < 0.001）；ST - 5与俯卧位之间为-2.46±1.67 mmHg（P < 0.001）；坐位与俯卧位之间为-3.22±1.56 mmHg（P < 0.001）。结果显示，在ST - 5位眼压显著升高，这表明需要进行此类测量，以试图解释眼压看似正常的患者青光眼的进展情况。
