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健康眼的角膜厚度评估：两种不同的 Scheimpflug 设备的比较。

Corneal thickness evaluation in healthy eyes: Comparison between two different Scheimpflug devices.

机构信息

Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana" University of Salerno, Baronissi, Salerno, Italy.

Corneal Transplant Unit, ASL Napoli 1, Naples, Italy.

出版信息

PLoS One. 2020 Dec 3;15(12):e0243370. doi: 10.1371/journal.pone.0243370. eCollection 2020.

DOI:10.1371/journal.pone.0243370
PMID:33270786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7714349/
Abstract

PURPOSE

To evaluate the correlation between corneal thickness (CT) measurements obtained with two Scheimpflug devices, Pentacam HR and Precisio, and to elaborate, if necessary, a regression formula which could make these results comparable.

DESIGN

Retrospective, Comparative, Observational study.

SETTING

Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana" University of Salerno, Italy.

METHODS

One hundred twenty four healthy eyes of 124 volunteers (65 males; range: 20-32 years; mean age of 24.8 ± 1.7) were included in this study. CT was measured using Pentacam HR and Precisio in three different points: the pupil center (PC), the corneal apex (CA) and the thinnest point (TP).

RESULTS

CT obtained with both devices at the PC, at the CA and at the TP showed a good correlation (r = 0.97, r = 0.97, r = 0.97, respectively), but Pentacam HR measurements were significantly thicker than those provided by Precisio (p < 0.01). The differences between Pentacam HR and Precisio were 21.9 ± 8.8 μm at the PC, 21.9 ± 8.9 μm at the CA, 19.1 ± 9.0 μm at the TP. The calculated regression formulas were: y = 0.9558x + 2.3196 for the PC, y = 0.9519x + 4.5626 for the CA, y = 0.9364x + 15.436 for the TP, where x is the CT measured with Pentacam HR and y is the Precisio measurement.

CONCLUSIONS

The findings provided by this study highlight that Precisio measures thinner corneas compared to Pentacam HR. The identified regression formulas could be utilized to make interchangeable the results obtained with these two devices.

摘要

目的

评估两种 Scheimpflug 设备（Pentacam HR 和 Precisio）测量的角膜厚度（CT）之间的相关性，并制定必要的回归公式，使这些结果具有可比性。

设计

回顾性、对比、观察性研究。

地点

意大利萨勒诺“斯卡莱莫萨伦蒂纳”大学医学、外科学和牙科学院。

方法

本研究纳入了 124 名志愿者的 124 只健康眼（65 名男性；年龄范围：20-32 岁；平均年龄 24.8 ± 1.7 岁）。使用 Pentacam HR 和 Precisio 在三个不同点（瞳孔中心 [PC]、角膜顶点 [CA] 和最薄点 [TP]）测量 CT。

结果

两种设备在 PC、CA 和 TP 处测量的 CT 具有良好的相关性（r = 0.97、r = 0.97、r = 0.97），但 Pentacam HR 测量值明显高于 Precisio（p < 0.01）。Pentacam HR 和 Precisio 之间的差异分别为 PC 处 21.9 ± 8.8 μm、CA 处 21.9 ± 8.9 μm、TP 处 19.1 ± 9.0 μm。计算得出的回归公式为：PC 处 y = 0.9558x + 2.3196、CA 处 y = 0.9519x + 4.5626、TP 处 y = 0.9364x + 15.436，其中 x 为 Pentacam HR 测量的 CT，y 为 Precisio 测量值。

结论

本研究结果表明，与 Pentacam HR 相比，Precisio 测量的角膜更薄。确定的回归公式可用于使这两种设备的结果具有互换性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/7ea68e68951c/pone.0243370.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/946a8b830426/pone.0243370.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/af33b173df11/pone.0243370.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/4a41a125fd05/pone.0243370.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/5328baaca95a/pone.0243370.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/4cf961fb507e/pone.0243370.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/7ea68e68951c/pone.0243370.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/946a8b830426/pone.0243370.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/af33b173df11/pone.0243370.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/4a41a125fd05/pone.0243370.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/5328baaca95a/pone.0243370.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/4cf961fb507e/pone.0243370.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56a1/7714349/7ea68e68951c/pone.0243370.g006.jpg

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