De Bernardo Maddalena, Pilone Vincenzo, Di Paola Ilenia, Cione Ferdinando, Cembalo Giovanni, Calabrese Pietro, Rosa Nicola
Eye Unit, Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84084 Salerno, Italy.
Unit of General, Emergency and Bariatric Surgery, Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84084 Salerno, Italy.
J Clin Med. 2023 Sep 10;12(18):5883. doi: 10.3390/jcm12185883.
Comparing intraocular pressure (IOP) changes (ΔIOP) between obese subjects and non-obese controls in relation to different positions: standing, sitting, supine.
the IOP was measured in both obese patients and non-obese controls groups with Tono-Pen AVIA in different positions following this sequence: after 5 min (5') in the standing position, sitting, supine, supine after 5 min (supine 5') and immediately after standing. ΔIOP values obtained comparing all positions were, therefore, evaluated.
92 eyes of 46 obese subjects aged between 18 and 59 years (mean 38.07 ± 11.51 years) and of a Body Mass Index (BMI) between 31.84 and 60.65 (mean 41.84 ± 7.05) were evaluated. A total of 48 eyes of 24 non-obese controls aged between 23 and 55 (mean 35.21 ± 11.96 years) and of a BMI between 18.20 and 26.79 (mean 21.04 ± 2.36) were also recruited. In obese subjects, there were statistically significant differences between the IOP in the supine position and the supine positions 5' with all other IOP measurements ( < 0.05). There were statistically significant differences between ΔIOP in both supine positions and prolonged standing positions obtained by obese subjects and non-obese controls ( < 0.05).
In obese subjects, there is a statistically significant increase in IOP in the supine positions that is significantly greater than the non-obese population. BMI is weakly correlated with IOP and ΔIOP in postural changes.
比较肥胖受试者和非肥胖对照组在不同体位（站立、坐着、仰卧）下的眼压（IOP）变化（ΔIOP）。
使用托诺笔AVIA眼压计，按照以下顺序在肥胖患者和非肥胖对照组的不同体位下测量眼压：站立5分钟后、坐着、仰卧、仰卧5分钟后以及站立后立即测量。因此，评估了比较所有体位获得的ΔIOP值。
评估了46名年龄在18至59岁（平均38.07±11.51岁）、体重指数（BMI）在31.84至60.65之间（平均41.84±7.05）的肥胖受试者的92只眼睛。还招募了24名年龄在23至55岁（平均35.21±11.96岁）、BMI在18.20至2.79之间（平均21.04±2.36）的非肥胖对照组的48只眼睛。在肥胖受试者中，仰卧位眼压与仰卧5分钟后的眼压以及所有其他眼压测量值之间存在统计学显著差异（<0.05）。肥胖受试者和非肥胖对照组在仰卧位和长时间站立位获得的ΔIOP之间存在统计学显著差异（<0.05）。
在肥胖受试者中，仰卧位眼压有统计学显著升高，且明显高于非肥胖人群。BMI与体位变化时的眼压和ΔIOP呈弱相关。
