Lee Chia-Yi, Chen Hung-Chi, Lian Ie-Bin, Huang Jing-Yang, Yang Shun-Fa, Chang Chao-Kai
Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Nobel Eye Institute, Taipei 10041, Taiwan.
Diagnostics (Basel). 2024 Aug 7;14(16):1717. doi: 10.3390/diagnostics14161717.
We aimed to survey the potential correlation between biometric parameters and postoperative outcomes after implanting extended depth-of-focus (EDOF) intraocular lenses (IOLs) and trifocal IOLs. A retrospective cohort study was conducted, and patients receiving EDOF or trifocal IOL implantations were included. In total, 36 and 26 eyes were enrolled in the EDOF and trifocal groups, respectively. The primary outcomes of this study were the postoperative uncorrected distance visual acuity (UDVA), uncorrected near visual acuity (UNVA), and spherical equivalent (SE). The generalized linear model was applied to evaluate the adjusted odds ratio (aOR) and 95% confidence intervals (CIs) of primary outcomes in patients with different biometric characters. The final UDVA of the EDOF group was significantly better than that of the trifocal group ( = 0.020), and the UNVA and SE did not show significant differences between the two groups throughout the postoperative period (all > 0.05). In a multivariable analysis, the UDVA was significantly better in the EDOF group than in the trifocal group ( = 0.038). For the subgroup analysis, the high axial length (AXL) value correlated to a lower postoperative UDVA in the EDOF group (both < 0.05). Additionally, a large white-to-white (WTW) diameter was related to worse postoperative UNVA in the trifocal group ( = 0.042), and a high AXL was associated with higher SE in both the EDOF and trifocal groups (both < 0.05). In conclusion, a high AXL correlates to worse postoperative outcomes in both the EDOF and trifocal IOLs, and trifocal IOL outcomes could be affected by large WTW diameters.
我们旨在调查植入扩展景深（EDOF）人工晶状体（IOL）和三焦点IOL后生物特征参数与术后结果之间的潜在相关性。进行了一项回顾性队列研究，纳入接受EDOF或三焦点IOL植入的患者。EDOF组和三焦点组分别纳入了36只眼和26只眼。本研究的主要结果是术后未矫正远视力（UDVA）、未矫正近视力（UNVA）和等效球镜度（SE）。应用广义线性模型评估不同生物特征患者主要结果的调整优势比（aOR）和95%置信区间（CI）。EDOF组的最终UDVA显著优于三焦点组（ = 0.020），并且在整个术后期间，两组之间的UNVA和SE均未显示出显著差异（均 > 0.05）。在多变量分析中，EDOF组的UDVA显著优于三焦点组（ = 0.038）。对于亚组分析，在EDOF组中，高眼轴长度（AXL）值与较低的术后UDVA相关（均 < 0.05）。此外，在三焦点组中，较大的白对白（WTW）直径与较差的术后UNVA相关（ = 0.042），并且在EDOF组和三焦点组中，高AXL均与较高的SE相关（均 < 0.05）。总之，高AXL与EDOF和三焦点IOL术后较差的结果相关，并且三焦点IOL的结果可能受到较大WTW直径的影响。
