Kim Sung-Dong, Jung Da-Woon, Lee Jung-Woo, Park Ji-Hwan, Mun Sue-Jean, Cho Kyu-Sup
Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea.
Department of Otorhinolaryngology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Am J Otolaryngol. 2021 Nov-Dec;42(6):103079. doi: 10.1016/j.amjoto.2021.103079. Epub 2021 May 14.
Nasal obstruction is common in patients with obstructive sleep apnea (OSA). Nonetheless, the effectiveness of isolated nasal surgery in treatment of OSA remains controversial. This study is to evaluate the subjective and objective outcome after isolated nasal surgery in patients with OSA and to determine the associated factors related to the success rate of isolated nasal surgery.
The study population consisted of 35 patients with nasal obstruction who had been diagnosed with OSA and were undergoing septoplasty and inferior turbinate reduction to correct nasal pathologies. Preoperative drug-induced sleep endoscopy was performed to evaluate the obstruction site. Patients were assessed before and after nasal surgery using subjective outcomes measures, including the Visual Analog Scale and Epworth Sleepiness Scale, as well as by overnight polysomnography.
All patients experienced improved nasal breathing postoperatively. At 6 months postoperatively, patients exhibited significant symptomatic improvement in snoring, sleep apnea, morning headache, tiredness, and daytime sleepiness. Postoperative polysomnography revealed significant improvement in the apnea-hypopnea index, respiratory disturbance index, and percentage of time with oxygen saturation < 90%. Although the overall success rate of nasal surgery alone was 14.3%, the criteria for success were met in 50% of patients with allergic rhinitis. Furthermore, the success rate was significantly higher in patients with moderate to severe nasal obstruction than in patients with mild nasal obstruction.
Among patients with OSA, those with allergic rhinitis and severe nasal obstruction are likely to have a better surgical outcome following isolated nasal surgery.
鼻塞在阻塞性睡眠呼吸暂停(OSA)患者中很常见。尽管如此,单纯鼻手术治疗OSA的有效性仍存在争议。本研究旨在评估单纯鼻手术治疗OSA患者后的主观和客观结果,并确定与单纯鼻手术成功率相关的因素。
研究人群包括35例被诊断为OSA且因鼻塞而接受鼻中隔成形术和下鼻甲切除术以纠正鼻腔病变的患者。术前进行药物诱导睡眠内镜检查以评估阻塞部位。使用主观结果测量方法,包括视觉模拟量表和爱泼华嗜睡量表,以及通过整夜多导睡眠图对患者进行鼻手术前后的评估。
所有患者术后鼻呼吸均有改善。术后6个月,患者在打鼾、睡眠呼吸暂停、晨起头痛、疲劳和日间嗜睡方面有显著的症状改善。术后多导睡眠图显示呼吸暂停低通气指数、呼吸紊乱指数以及血氧饱和度<90%的时间百分比有显著改善。尽管单纯鼻手术的总体成功率为14.3%,但50%的变应性鼻炎患者达到了成功标准。此外,中重度鼻塞患者的成功率显著高于轻度鼻塞患者。
在OSA患者中,变应性鼻炎和严重鼻塞患者在单纯鼻手术后可能有更好的手术结果。