Scarabosio Anna, Surico Pier Luigi, Patanè Luca, Tambasco Damiano, Kahale Francesca, Zeppieri Marco, Parodi Pier Camillo, Coassin Marco, Di Zazzo Antonio
Department of Plastic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Department of Plastic Surgery, University Hospital of Udine, 33100 Udine, Italy.
Diagnostics (Basel). 2024 Aug 21;14(16):1828. doi: 10.3390/diagnostics14161828.
Floppy Eyelid Syndrome (FES) is an underdiagnosed ocular condition characterized by the abnormal laxity of the upper eyelids, often leading to chronic eye irritation and redness. This review provides an in-depth examination of FES, covering its pathophysiology, clinical presentation, and diagnostic and therapeutic approaches. We discuss the potential etiological factors, including genetic predispositions and associations with ocular and systemic conditions such as obesity, obstructive sleep apnea, keratoconus, and glaucoma. Diagnostic strategies are outlined, emphasizing the importance of thorough clinical examinations and specific tests for an efficacious grading and assessment of FES. Management of FES ranges from conservative medical treatments to surgical interventions for more severe cases and should be driven by a comprehensive and multidisciplinary approach. Herein, we illustrate the practical aspects of diagnosing and managing this condition. This comprehensive review aims to enhance the recognition and treatment of FES, ultimately improving the quality of life for affected patients.
睑皮松弛综合征（FES）是一种诊断不足的眼部疾病，其特征为上睑异常松弛，常导致慢性眼部刺激和发红。本综述对睑皮松弛综合征进行了深入研究，涵盖其病理生理学、临床表现以及诊断和治疗方法。我们讨论了潜在的病因因素，包括遗传易感性以及与肥胖、阻塞性睡眠呼吸暂停、圆锥角膜和青光眼等眼部及全身疾病的关联。概述了诊断策略，强调了全面临床检查和特定检测对于有效分级和评估睑皮松弛综合征的重要性。睑皮松弛综合征的管理范围从保守的药物治疗到针对更严重病例的手术干预，应采用全面的多学科方法。在此，我们阐述了诊断和管理该疾病的实际方面。这一全面综述旨在提高对睑皮松弛综合征的认识和治疗水平，最终改善受影响患者的生活质量。
