Department of Ophthalmology, Long School of Medicine, University of Texas Health at San Antonio, San Antonio, TX, USA.
Department of Ophthalmology, Long School of Medicine, University of Texas Health at San Antonio, San Antonio, TX, USA.
Ocul Surf. 2020 Jan;18(1):31-39. doi: 10.1016/j.jtos.2019.10.002. Epub 2019 Oct 5.
Floppy eyelid syndrome (FES) is defined as eyelid hyperlaxity with reactive palpebral conjunctivitis. It is a common condition that can be associated with significant ocular irritation. FES presents with easily everted eyelids and chronic papillary conjunctivitis in the upper eyelids. It is frequently associated with ocular and systemic diseases, notably keratoconus and obstructive sleep apnea, respectively. This comprehensive review describes the epidemiology, pathological changes, proposed pathogenesis, clinical manifestations, and a variety of treatment options for this condition. Conservative treatment of FES includes aggressive lubrication, nighttime eye shield, and avoiding sleeping on the affected eye. Patients with FES and obstructive sleep apnea may have an improvement in their ocular signs and symptoms after long-term therapy with continuous positive airway pressure. In refractory cases, a corrective surgery that addresses the eyelid laxity can result in significant improvement. All patients with ocular irritation should be evaluated for the presence of FES.
眼睑松弛综合征（FES）定义为伴有反应性睑结膜炎症的眼睑过度松弛。它是一种常见病症，可引起明显的眼部刺激。FES 的表现为眼睑容易外翻和上眼睑慢性乳头性结膜炎。它常与眼部和全身疾病相关，分别为圆锥角膜和阻塞性睡眠呼吸暂停。本综述描述了该病的流行病学、病理变化、提出的发病机制、临床表现以及多种治疗选择。FES 的保守治疗包括积极的润滑、夜间眼罩和避免在受影响的眼睛上睡觉。阻塞性睡眠呼吸暂停合并 FES 的患者在接受持续气道正压治疗后，其眼部体征和症状可能会有所改善。对于难治性病例，矫正眼睑松弛的手术可显著改善病情。所有有眼部刺激的患者都应评估是否存在 FES。
