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冠状动脉旁路移植术后的长期生存——环境温度重要吗?

Long-Term Survival after Coronary Artery Surgical Revascularization-Does Ambient Temperature Matter?

机构信息

Cardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-701 Poznan, Poland.

Institute of Environmental Protection-National Research Institute, 02-170 Warsaw, Poland.

出版信息

Medicina (Kaunas). 2024 Jul 27;60(8):1220. doi: 10.3390/medicina60081220.

Abstract

The progression of global warming results in an increased exposure to extreme heat, leading to exaggeration of preexisting diseases and premature deaths. The aim of the study was to present possible risk factors for all-cause long-term mortality in patients who underwent surgical revascularization, including an assessment of the influence of ambient temperature exposure. Retrospective analysis included 153 (123 (80%) males and 30 (20%) females) patients who underwent off-pump revascularization and were followed for a median time of 2533 (1035-3250) days. The demographical, clinical data and ambient temperature exposure were taken into analysis for prediction of all-cause mortality. Individual exposure was calculated based on the place of habitation. In the multivariate logistic regression model with backward stepwise elimination method, risk factors such as dyslipidaemia ( = 0.001), kidney disease ( = 0.005), age ( = 0.006), and body mass index ( = 0.007) were found to be significant for late mortality prediction. In addition to traditional factors, environmental characteristics, including tropical nights ( = 0.043), were revealed to be significant. High night-time ambient temperatures known as tropical nights may be regarded as additional long-term mortality risk factor after surgical revascularization.

摘要

全球变暖的加剧导致人们暴露在极端高温下的风险增加,从而加剧了原有疾病的恶化和过早死亡。本研究旨在探讨可能导致接受手术血运重建的患者全因长期死亡率的危险因素,包括评估环境温度暴露的影响。

回顾性分析纳入了 153 名(123 名男性(80%)和 30 名女性(20%))接受非体外循环血运重建的患者,中位随访时间为 2533(1035-3250)天。对人口统计学、临床数据和环境温度暴露进行分析,以预测全因死亡率。个体暴露是根据居住地计算的。

采用逐步后退的多变量逻辑回归模型,发现血脂异常( = 0.001)、肾脏疾病( = 0.005)、年龄( = 0.006)和体重指数( = 0.007)等危险因素对晚期死亡率的预测具有显著意义。除了传统因素外,环境特征,包括热带夜晚( = 0.043),也被证明是显著的。

众所周知,夜间高环境温度被称为热带夜晚,可能被视为手术血运重建后额外的长期死亡风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf40/11356662/dff6c8880f98/medicina-60-01220-g001.jpg

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