Turcu Teodora-Adela, Lescaie Andreea, Grama Andreea Rodica, Strătulă Andreea-Cătălina, Vincene Andreea-Iasmina, Grigoraș Laura-Maria, Jităreanu Cristina, Babeu Alina Maria, Gafencu Mihai, Crăciun Maria-Dorina, Chivu Carmen-Daniela, Baconi Daniela Luiza, Mihai Cristina Maria, Ulmeanu Coriolan Emil, Nițescu Gabriela Viorela
Department of Pediatrics, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Pediatric Poison Centre, "Grigore Alexandrescu" Clinical Emergency Hospital for Children, 017443 Bucharest, Romania.
Life (Basel). 2024 Aug 20;14(8):1033. doi: 10.3390/life14081033.
This six-year multicentre study investigated acute intentional poisoning with substances of abuse in adolescents to identify changes and patterns in substance use. Data from 562 adolescents were collected from three paediatric poison centres in Romania between January 2017 and December 2022. This study analysed the epidemiological and sociodemographic characteristics of the adolescents, including age, gender, place of residence, history of substance abuse, psychiatric history, and history of institutionalised care. The findings revealed that cannabis and new psychoactive substances (NPSs) are the most commonly implicated substances, each with distinct profiles among adolescents. Cannabis was involved in 46.1% of cases, with a significant association with urban residency. NPSs were identified as the second most prevalent substance, accounting for 39.3% of cases. These were more prevalent in rural areas and among patients with psychiatric disorders. Cannabis and NPSs were also the most commonly implicated substances in acute intentional poisoning cases with substances of abuse. These substances have distinct profiles among adolescents, including age, gender, residency area, history of substance abuse, psychiatric history, and institutional care. These findings underscore the necessity of targeted public health interventions and integrated care approaches to address substance use and related mental health issues in adolescents.
这项为期六年的多中心研究调查了青少年急性故意滥用药物中毒情况，以确定药物使用的变化和模式。2017年1月至2022年12月期间，从罗马尼亚的三个儿科中毒中心收集了562名青少年的数据。本研究分析了青少年的流行病学和社会人口学特征，包括年龄、性别、居住地点、药物滥用史、精神病史和机构护理史。研究结果显示，大麻和新型精神活性物质（NPS）是最常涉及的物质，在青少年中各有不同特征。大麻涉及46.1%的病例，与城市居住显著相关。NPS被确定为第二常见物质，占病例的39.3%。这些物质在农村地区和患有精神疾病的患者中更为普遍。大麻和NPS也是急性故意滥用药物中毒病例中最常涉及的物质。这些物质在青少年中有不同特征，包括年龄、性别、居住地区、药物滥用史、精神病史和机构护理情况。这些发现强调了有针对性的公共卫生干预措施和综合护理方法对于解决青少年药物使用及相关心理健康问题的必要性。
