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探索全身麻醉下绵羊泪腺的泪液分泌:研究使用1%透明质酸钠眼用凝胶的潜在影响。

Exploring Lacrimal Gland Tear Production in Sheep under General Anesthesia: Examining the Potential Impact of Utilizing 1% Hyaluronic Acid Ophthalmic Gel.

作者信息

Pavel Ruxandra, Ene Ioana, Costea Ruxandra

机构信息

Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 011464 Bucharest, Romania.

出版信息

Life (Basel). 2024 Aug 20;14(8):1038. doi: 10.3390/life14081038.

Abstract

The aim of the study is to assess the lacrimal gland tear production, using the Schirmer Tear Test (STT), in healthy sheep under general anesthesia and to explore the effects of applying 1% hyaluronic acid ophthalmic gel during general anesthesia. While STT values during anesthesia have been well documented in small animals such as cats and dogs, there seems to be a lack of information available for ruminants like sheep. This gap in the literature highlights the need for further research and exploration into tear production in sheep under anesthesia. The experimental research conducted on twelve adults female sheep provided valuable insights into tear production under anesthesia. By assessing tear production at various key time points the study was able to capture the changes in tear production throughout anesthesia and revealed a significant decrease in Schirmer Tear Test values in all sheep, following general anesthesia. The results showed that closing and taping the eye yielded determined better outcomes compared to administering a 1% lubricant ophthalmic gel. This finding suggests that eye care during anesthesia can impact tear production in sheep.

摘要

本研究的目的是在全身麻醉下,使用泪液分泌试验(STT)评估健康绵羊的泪腺泪液分泌情况,并探讨在全身麻醉期间应用1%透明质酸钠眼用凝胶的效果。虽然麻醉期间的STT值在猫和狗等小动物中已有充分记录,但对于绵羊等反刍动物似乎缺乏可用信息。文献中的这一空白凸显了进一步研究和探索绵羊麻醉下泪液分泌情况的必要性。对12只成年雌性绵羊进行的实验研究为麻醉下的泪液分泌提供了有价值的见解。通过在各个关键时间点评估泪液分泌,该研究能够捕捉到整个麻醉过程中泪液分泌的变化,并显示所有绵羊在全身麻醉后泪液分泌试验值均显著下降。结果表明,与使用1%润滑性眼用凝胶相比,闭眼并包扎眼睛能产生更好的效果。这一发现表明,麻醉期间的眼部护理会影响绵羊的泪液分泌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28db/11355265/94ea31d9eba8/life-14-01038-g001.jpg

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