Di Pierro Francesco, Zerbinati Nicola, Cazzaniga Massimiliano, Bertuccioli Alexander, Palazzi Chiara Maria, Cavecchia Ilaria, Matera Mariarosaria, Labrini Edoardo, Sagheddu Valeria, Soldi Sara
Microbiota International Clinical Society, 10123 Torino, Italy.
Scientific & Research Department, Velleja Research, 20125 Milano, Italy.
Microorganisms. 2024 Aug 9;12(8):1626. doi: 10.3390/microorganisms12081626.
Recent investigations have highlighted, both experimentally and clinically, that probiotic strains equipped with arabinofuranosidase, in particular and , favor regular intestinal motility, thus counteracting constipation. By analyzing the gene expression and the proliferative response in the presence of arabinan of the probiotic W11, a strain previously validated as an anti-constipation probiotic, we have speculated that its response mechanism to arabinan can effectively explain its clinical action. Our approach could be used in the future to select probiotics endowed with arabinofuranosidase-related anti-constipation effects.
最近的研究在实验和临床方面都突出表明，配备阿拉伯呋喃糖苷酶的益生菌菌株，尤其是[具体菌株1]和[具体菌株2]，有助于肠道正常蠕动，从而缓解便秘。通过分析益生菌W11（一种先前已被验证具有抗便秘作用的益生菌）在阿拉伯聚糖存在时的基因表达和增殖反应，我们推测其对阿拉伯聚糖的反应机制可以有效解释其临床作用。我们的方法未来可用于筛选具有阿拉伯呋喃糖苷酶相关抗便秘作用的益生菌。
