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抗支原体疫苗研发的研究进展

Research Progress in the Development of Vaccines against Mycoplasma and Mycoplasma .

作者信息

Wu Shaopeng, Wang Miaoli, Yang Xiaoxue, Zhao Lu, Lan Zouran, Sun Shuhong

机构信息

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China.

Shandong Provincial Center for Animal Disease Control, Jinan 250010, China.

出版信息

Microorganisms. 2024 Aug 17;12(8):1699. doi: 10.3390/microorganisms12081699.

Abstract

Mycoplasma (MG) and Mycoplasma (MS) are the primary agents responsible for mycoplasma disease in poultry. MG has been identified as a significant cause of chronic respiratory disease in chickens, while MS has been linked to the development of tenosynovitis, joint swelling and other symptoms in chickens, leading to considerable economic losses for the poultry industry. Unfortunately, there is no specific drug for treatment and vaccination is the most important way to control the disease. There are some different types of vaccines, including live vaccines, inactivated vaccines, sub-unit vaccines and vector vaccines. This paper provides a comprehensive review of the development of vaccines for MG and MS.

摘要

鸡败血支原体(MG)和滑液支原体(MS)是引起家禽支原体病的主要病原体。MG已被确认为鸡慢性呼吸道疾病的重要病因,而MS与鸡腱鞘炎、关节肿胀及其他症状的发生有关,给家禽业造成了巨大经济损失。不幸的是,目前尚无特效治疗药物,疫苗接种是控制该病的最重要手段。疫苗有多种类型,包括活疫苗、灭活疫苗、亚单位疫苗和载体疫苗。本文对MG和MS疫苗的研发进行了全面综述。

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