Onisor Danusia, Brusnic Olga, Mocan Simona, Stoian Mircea, Avram Calin, Boicean Adrian, Dobru Daniela
Department of Internal Medicine VII, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, Gheorghe Marinescu Street No. 38, 540139 Targu Mures, Romania.
Gastroenterology Department, Mureș County Clinical Hospital, 540103 Targu Mures, Romania.
Pathogens. 2024 Aug 2;13(8):650. doi: 10.3390/pathogens13080650.
The role of cytomegalovirus (CMV) in the flare-up of ulcerative colitis (UC) is not clearly understood. CMV can cause similar symptoms in different clinical contexts, which may be attributed to the natural evolution of the viral infection, the patient's immune status, or its association with inflammatory bowel disease (IBD). This study aims to delineate the diverse manifestations of CMV-related lesions from clinical, endoscopic, and histopathological perspectives, alongside a brief narrative review of the literature. In managing IBD patients, it is crucial to be vigilant for signs of CMV reactivation, especially before the initiation of more intensive therapies.
巨细胞病毒（CMV）在溃疡性结肠炎（UC）发作中的作用尚不清楚。CMV在不同临床情况下可引起相似症状，这可能归因于病毒感染的自然演变、患者的免疫状态或其与炎症性肠病（IBD）的关联。本研究旨在从临床、内镜和组织病理学角度描述CMV相关病变的多样表现，并对文献进行简要叙述性综述。在管理IBD患者时，对CMV再激活的迹象保持警惕至关重要，尤其是在开始更强化治疗之前。
