2021年至2023年韩国美军基地的日本脑炎病毒监测

Japanese Encephalitis Virus Surveillance in U.S. Army Installations in the Republic of Korea from 2021 to 2023.

作者信息

Lado Paula, Crispell Gary P, Chong Sung Tae, Kim Myong Sun, Esparza Ashley N, Zielinski Eric, Iwami Akira, Williams Kelly P, Eads John J, Jimbo Kei, Mitzel Dana N, Cohnstaedt Lee W, Richardson Joshua B, Kugelman Jeffrey R, Stoops Craig A

机构信息

National Bio and Agro-Defense Facility, USDA Agricultural Research Service (ARS), P.O. Box 1807, Manhattan, KS 66505, USA.

Environmental Molecular Biology Laboratory, U.S. Army Public Health Command-Pacific, Camp Zama, Zama City 252-0027, Kanagawa, Japan.

出版信息

Pathogens. 2024 Aug 20;13(8):705. doi: 10.3390/pathogens13080705.

DOI:10.3390/pathogens13080705

PMID:39204305

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357451/

Abstract

Japanese encephalitis is a disease caused by the Japanese encephalitis virus (JEV) and is a concern for U.S. military personnel stationed in the Republic of Korea (ROK). The recent literature reports a potential shift from GI to GV as the dominant genotype circulating in east Asia. In the ROK, GV has been reported in a few spp., but not in the main JEV vector, . . The goal of this surveillance was to shed light on the current knowledge of the epidemiology of JEV in the ROK by analyzing mosquito collection data from three consecutive years, 2021-2023, and molecularly detecting and genotyping JEV in all spp. collected in several military locations across the ROK. In this study, we detected only JEV GI in . in 2021 samples. In contrast, all 2022 and 2023 positive samples were GV and detected in . , . , and . . Results support a shift in JEV genotype in the ROK and suggest that for GV, spp. other than . may be playing an important role.

摘要

日本脑炎是一种由日本脑炎病毒（JEV）引起的疾病，是驻大韩民国（韩国）的美国军事人员所关注的问题。最近的文献报道，在东亚地区传播的主要基因型可能正在从GI型向GV型转变。在韩国，已在少数物种中报告发现GV型，但在主要的日本脑炎病毒传播媒介中未发现……本监测的目的是通过分析2021年至2023年连续三年的蚊虫采集数据，并对在韩国多个军事地点采集的所有物种中的日本脑炎病毒进行分子检测和基因分型，以了解韩国日本脑炎病毒流行病学的现有知识。在本研究中，我们在2021年的样本中仅在……检测到日本脑炎病毒GI型。相比之下，2022年和2023年所有阳性样本均为GV型，且在……、……和……中检测到。结果支持韩国日本脑炎病毒基因型的转变，并表明对于GV型，除……之外的其他物种可能正在发挥重要作用。