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利用初始心电图预测急性心肌梗死的院内并发症。

Use of the initial electrocardiogram to predict in-hospital complications of acute myocardial infarction.

作者信息

Brush J E, Brand D A, Acampora D, Chalmer B, Wackers F J

出版信息

N Engl J Med. 1985 May 2;312(18):1137-41. doi: 10.1056/NEJM198505023121801.

Abstract

We evaluated the initial electrocardiogram as a predictor of complications in 469 patients with suspected acute myocardial infarction. An electrocardiogram was classified as positive if it showed one or more of the following: evidence of infarction, ischemia, or strain; left ventricular hypertrophy; left bundle-branch block; or paced rhythm. Forty-two (14 per cent) of 302 patients with positive electrocardiograms had at least one life-threatening complication (ventricular fibrillation, sustained ventricular tachycardia, or heart block), as compared with 1 (0.6 per cent) of 167 patients with a negative electrocardiogram. Life-threatening complications were therefore 23 times more likely if the initial electrocardiogram was positive (P less than 0.001). Other complications were 3 to 10 times more likely (P less than 0.01), interventions were 4 to 10 times more likely (P less than 0.05), and death was 17 times more likely (P less than 0.001) in patients with a positive electrocardiogram. We conclude that patients with a negative initial electrocardiogram have a low likelihood of complications and could be admitted to an intermediate care unit instead of a coronary care unit. This would reduce admissions to the coronary care unit by 36 per cent and thereby save considerable hospital costs without compromising patient care.

摘要

我们对469例疑似急性心肌梗死患者的初始心电图进行评估,以预测并发症。若心电图出现以下一项或多项表现,则分类为阳性:梗死、缺血或劳损迹象;左心室肥厚;左束支传导阻滞;或起搏心律。302例心电图阳性患者中有42例(14%)至少发生了一种危及生命的并发症(心室颤动、持续性室性心动过速或心脏传导阻滞),相比之下,167例心电图阴性患者中只有1例(0.6%)发生此类情况。因此,初始心电图呈阳性时,发生危及生命并发症的可能性要高23倍(P<0.001)。心电图阳性患者发生其他并发症的可能性高3至10倍(P<0.01),接受干预的可能性高4至10倍(P<0.05),死亡可能性高17倍(P<0.001)。我们得出结论,初始心电图阴性的患者发生并发症的可能性较低,可以入住中级护理病房而非冠心病监护病房。这将使冠心病监护病房的入院人数减少36%,从而在不影响患者护理的情况下节省可观的医院费用。

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