Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia.
Colorectal Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz, Jalan Yaacob Latiff, Bandar Tun Razak, 56000, Cheras, Wilayah Persekutuan Kuala Lumpur, Malaysia.
Asian Pac J Cancer Prev. 2024 Aug 1;25(8):2895-2904. doi: 10.31557/APJCP.2024.25.8.2895.
This study aimed to investigate the effect of Pilates exercise on the quality of life, functional capacity, cancer-related fatigue, depression and salivary cortisol of colorectal cancer survivors.
This is a quasi-experimental study which was conducted at Hospital Canselor Tuanku Muhriz, Universiti Kebangsaan Malaysia (UKM), and Hospital Al-Sultan Abdullah, Universiti Teknologi MARA (UiTM), Malaysia. The intervention group performed Pilates exercises with a certified Pilates instructor for eight weeks via online streaming from the participants' homes. Meanwhile, the control group participants received the usual care as stipulated by their oncologists. The primary outcome was the quality of life. The secondary outcomes were functional capacity, cancer-related fatigue, depression and salivary cortisol. Data was collected at baseline and eight weeks after the exercise intervention. The effects of the intervention were analyzed using Repeated Measures Analysis of Covariance (ANCOVA) statistical test.
Thirty-six (36) colorectal cancer survivors were allocated into either a Pilates exercise intervention group (N= 18) or a control group (N= 18). Over eight weeks, the Pilates exercise group revealed significant group x time interactions in terms of quality of life (p = 0.003), role functioning (p = 0.012), functional capacity (p = 0.048), and stool frequency (p = 0.021). However, only the stool frequency symptom (p = 0.008) remained significant after controlling for the confounders of age, gender and stage of cancer. No significant changes in cancer-related fatigue, depression and salivary cortisol levels between the groups were observed after the intervention.
Pilates exercise had positive impacts on role functioning, bowel function, and functional capacity among colorectal cancer survivors, ultimately contributing to an improvement in quality of life.
本研究旨在探讨普拉提运动对结直肠癌幸存者生活质量、功能能力、癌因性疲劳、抑郁和唾液皮质醇的影响。
这是一项准实验研究，在马来西亚国民大学（UKM）的 Canselor Tuanku Muhriz 医院和马来西亚玛拉工艺大学（UiTM）的 Al-Sultan Abdullah 医院进行。干预组通过在家中在线流媒体的方式，由认证的普拉提教练进行八周的普拉提运动。同时，对照组参与者接受其肿瘤医生规定的常规护理。主要结局为生活质量。次要结局为功能能力、癌因性疲劳、抑郁和唾液皮质醇。在基线和运动干预八周后收集数据。采用重复测量方差分析（ANCOVA）统计检验分析干预效果。
36 名（36 名）结直肠癌幸存者被分配到普拉提运动干预组（N=18）或对照组（N=18）。在八周的时间里，普拉提运动组在生活质量（p=0.003）、角色功能（p=0.012）、功能能力（p=0.048）和排便频率（p=0.021）方面表现出显著的组间时间交互作用。然而，在控制年龄、性别和癌症分期等混杂因素后，只有排便频率症状（p=0.008）仍然显著。干预后两组间癌因性疲劳、抑郁和唾液皮质醇水平均无显著变化。
普拉提运动对结直肠癌幸存者的角色功能、肠道功能和功能能力有积极影响，最终提高了生活质量。
